Wolfram Syndrome protein, Miner1, regulates sulphydryl redox status, the unfolded protein response, and Ca2+ homeostasis. [PDF]
, 2013 Miner1 is a redox-active 2Fe2S cluster protein. Mutations in Miner1 result in Wolfram Syndrome, a metabolic disease associated with diabetes, blindness, deafness, and a shortened lifespan.
Andreyev, Alexander Y +12 more
core +1 more source
Plants, 2021 (1) Background: Winter grazing of livestock poses significant environmental risks of nitrogen (N) leaching and sediment runoff. (2) Methods: A field study tested the effects of sowing catch crops of oats (Avena sativa L.), ryecorn (Secale cereale L.) or ...
Brendon Malcolm +8 more
doaj +1 more source
Is now the time for molecular driven therapy for diffuse large B-cell lymphoma? [PDF]
, 2017 INTRODUCTION: Recent genetic and molecular discoveries regarding alterations in diffuse large B-cell lymphoma (DLBCL) deeply changed the approach to this lymphoproliferative disorder.
Ansuinelli, Michela +4 more
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Journal of Animal Science, 2020 Abstract An experiment was conducted during the winter of two consecutive years to evaluate the effects of feeding green-chopped cool-season forages on digestibility, ruminal fermentation, and blood parameters in beef steers. Nine ruminally cannulated Angus crossbred steers (year 1: 359 ± 79 kg; year 2: 481 ± 105 kg) received ad libitum ...
Tessa M Schulmeister +9 more
openaire +3 more sources
β-cell dysfunctional ERAD/ubiquitin/proteasome system in type 2 diabetes mediated by islet amyloid polypeptide-induced UCH-L1 deficiency. [PDF]
, 2010 ObjectiveThe islet in type 2 diabetes is characterized by β-cell apoptosis, β-cell endoplasmic reticulum stress, and islet amyloid deposits derived from islet amyloid polypeptide (IAPP).
Butler, Alexandra E +7 more
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Study on extruding process of grain concentrate mixture with chopped green mass of legumes
Вестник Донского государственного технического университета, 2016 The work objective is to study an advanced way of enhancing the nutritive value of the mixed feed by co-extrusion of the grain mixtures with chopped green legumes that differ in high content of vitamins and protein. The task of this investigation is an experimental determination of rational parameters and operating modes of the equipment for the ...
Evgeny A Pamfilov +4 more
openaire +3 more sources
Mifepristone increases mRNA translation rate, triggers the unfolded protein response, increases autophagic flux, and kills ovarian cancer cells in combination with proteasome or lysosome inhibitors [PDF]
, 2016 The synthetic steroid mifepristone blocks the growth of ovarian cancer cells, yet the mechanism driving such effect is not entirely understood. Unbiased genomic and proteomic screenings using ovarian cancer cell lines of different genetic backgrounds and
Callegari, Eduardo A. +13 more
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Productivity of different varieties of alfalfa in the south of the Rostov region
Зерновое хозяйство России, 2018 The work presents the assessment of productivity of such alfalfa varieties as ‘Rostovskaya 60’, ‘Rostovskaya 90’, ‘Lyutsiya’ and ‘Manycheskaya’ (of haymaking use) and ‘Kubanskaya zheltaya’ (of haymaking and grazing use).
S. A. Ignatiev +2 more
doaj +2 more sources
Regulation of podocyte survival and endoplasmic reticulum stress by fatty acids and its modification by Stearoyl-CoA desaturases and cyclic AMP [PDF]
, 2011 Podocyte apoptosis is a hallmark in the development and progression of diabetic nephropathy (DN). Several factors of the diabetic milieu are known to induce podocyte apoptosis. Currently, the role of free fatty acids (FFAs) for podocytopathy and podocyte
Sieber, Jonas
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The Photodetector Array Camera and Spectrometer (PACS) on the Herschel Space Observatory [PDF]
, 2010 The Photodetector Array Camera and Spectrometer (PACS) is one of the three science instruments on ESA's far infrared and submillimetre observatory. It employs two Ge:Ga photoconductor arrays (stressed and unstressed) with 16x25 pixels, each, and two ...
A. Contursi +113 more
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