Results 181 to 190 of about 4,413,578 (263)

Telomere‐to‐Telomere Genomes Reveal that Multiscale Evolution Shapes the Largest Metabolic Arsenal of Diaporthe Fungi

Advanced Science, EarlyView.
This study presents the first telomere‐to‐telomere genomes and population resources for Diaporthe pathogens, uncovering the largest known fungal repertoire of secondary metabolite gene clusters. Structural variations and horizontal gene transfer drive cluster diversification, while specific rapidly evolving clusters control virulence, offering novel ...
Kainan Li, Chen Zhang, Zhichao Zhang, Jiaheng Cheng, Qiuyan Gao, Long Gao, Xiaolin Zhao, Wei Yan, Yuanchao Wang, Wenwu Ye   +9 more
wiley   +1 more source

Exploring the potential targets and mechanisms of malachite green induced lung adenocarcinoma through network toxicology and molecular docking. [PDF]

Medicine (Baltimore)
Qu S, Yang Z, Zhang S, Hou Y.
europepmc   +1 more source

Zinc Exposure Causes Disulfidptosis to Induce Miscarriage by Up‐Regulating GATA1/METTL1/SLC7A11 Axis

Advanced Science, EarlyView.
Zn exposure up‐regulates GATA1, promoting GATA1‐mediated METTL1 and SLC7A11 transcription. It also enhances METTL1‐mediated m7G modification on SLC7A11 mRNA, increasing SLC7A11 mRNA stability. Ultimately, Zn exposure up‐regulates SLC7A11 at both transcriptional and post‐transcriptional levels, causing disulfidptosis. Knockdown of murine Slc7a11, Gata1,
Wenxin Huang, Yi Sun, Yanxin Wang, Haijun Yan, Xiaoping Yue, Weidong Wu, Xueyu Chen, Jinfang Zhang, Yanbing Lin, Qiong Lei, Nan Ji, Shuaishuai Xing, Liqin Zeng, Qingzheng Kang, Depeng Zhao, Geng Guo, Huidong Zhang   +16 more
wiley   +1 more source

Enhancing ocular accommodation function and intraocular pressure symmetry through Mingshi Qigong: A pilot case series on visual fatigue recovery. [PDF]

J Family Med Prim Care
Lin SY, Tsai CY, Kuo TBJ, Kung YY, Yang CCH.   +4 more
europepmc   +1 more source

Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser

Advanced Science, EarlyView.
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu, Aswathy Sundaresan, Nazire‐Begüm Kazkal, Clement Lafargue, Lior Zarfaty, Li‐Gang Wang, Ofek Birnholtz, Dominique Decanini, Melanie Lebental, Patrick Sebbah   +9 more
wiley   +1 more source

Spatiotemporal land use land cover dynamics and rainfall-runoff responses in the urbanizing Gdynia, Poland. [PDF]

Sci Rep
Galata AW, Gulshad K, Szydłowski M.
europepmc   +1 more source

Bifidobacterium Pseudolongum‐Derived Acetate Attenuates Acute Pancreatitis Through GPR43‐Mediated Suppression of M1 Macrophage Polarization

Advanced Science, EarlyView.
The severity of acute pancreatitis (AP) is linked to reduced abundance of Bifidobacterium pseudolongum (B. pseudolongum). Administration of B. pseudolongum or its key metabolite acetate alleviates pancreatic and systemic inflammation by suppressing M1 macrophage polarization.
Langyi Guan, Xueyang Li, Cong He, Pan Zheng, Yaoyu Zou, Qi Zhu, Xin Li, Jie Liang, Junmin Yang, Li Zhang, Yuman Ye, Jianhua Wan, Huajing Ke, Jianping Liu, Nonghua Lu, Nianshuang Li, Yin Zhu   +16 more
wiley   +1 more source

Molecular Techniques and Ecological Data for Taxonomically Difficult Groups: A Case Study of a Morphologically Variable New Species in the Genus <i>Chrysobothris</i> (Coleoptera: Buprestidae). [PDF]

Insects
Huang B, Wu L, Ni T, Su R, Song H, Wang R.   +5 more
europepmc   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Effect of noise and green space exposure on depression, anxiety and stress among the Lebanese population. [PDF]

PLoS One
Youssef R, Dassuki N, El Natour D, Al Achcar J, Maadarani R, Krayker G, Azakir B, El Masri J, Salameh P.   +8 more
europepmc   +1 more source