Results 61 to 70 of about 2,683,412 (297)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Green Economy for a Sustainable Future: Experience from the Visegrad Group Countries

open access: yesComparative Economic Research
The objective of this paper is to identify the significance of the green economy for a sustainable future and compare the situation and developments in achieving the European Green Deal (EGD) in the Visegrad Group (V4) countries.
Roman Klimko
doaj   +1 more source

The European Green Deal and the sustainable finance

open access: yes, 2022
openIl Green Deal Europeo è il piano economico a lungo termine che ha l’obiettivo di garantire al vecchio continente una crescita economica basata sulla sostenibilità ambientale attraverso una transazione verde, giusta e inclusiva.
ALBIERO, ANDREA
core  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Competences of public administration employees in the face of the challenges of the Green Deal [PDF]

open access: yesEdukacja Ustawiczna Dorosłych
The challenges of the climate change, environmental degradation and sustainability are becoming ever more pressing. In response to those issues, the European Union has launched an ambitious strategy known as the Green Deal. The aim of this strategy is to
Michał Ślusarczyk
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Barcelona reAct: Green deal [versió en català]

open access: yes, 2021
Subtítols en catalàEl Barcelona Green Deal és las nova agenda urbana i econòmica per a la propera dècada, adaptada a reptes com les transicions ecològica i digital, que s’han vist accelerats per la pandèmia. Un full de ruta que té la sostenibilitat com a
Gerència d'Àrea d'Economia, Recursos i Promoció Econòmica
core   +1 more source

The European Green Deal: New Opportunities for Port Cities?

open access: yes, 2020
With the European Green Deal made public last December, the new European Commission took the first steps to transforming Europe into the first climate neutral continent by 2050.
Hauser, S.J. (author)
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Perspectives in bioeconomy: strategies, Green Deal and Covid19

open access: yesForest@, 2020
The importance of a sustainable and circular bioeconomy in achieving the Sustainable Development Goals (SDGs) has been recognized at various political levels.
Marchetti M, Palahí M
doaj   +1 more source

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