Results 81 to 90 of about 1,811,626 (246)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

How do entrepreneurial traits affect green entrepreneurial performance? A Fuzzy set qualitative comparative analysis (fsQCA)

Results in Engineering
Green entrepreneurship has emerged as a critical research area, yet existing studies predominantly focus on the isolated impact of individual entrepreneurial traits on performance, overlooking the complex interplay of multiple factors, especially within ...
Ying Ding, Hong Yang, Can Peng, Chaolin Lyu   +3 more
doaj   +1 more source

Computers from plants we never made. Speculations

, 2017
We discuss possible designs and prototypes of computing systems that could be based on morphological development of roots, interaction of roots, and analog electrical computation with plants, and plant-derived electronic components.
A Adamatzky, A Adamatzky, A Adamatzky, A Trewavas, A Trewavas, AG Volkov, AJ Trewavas, BB Stone, BDL Costello, C Burbach, DB Strukov, E Lehtonen, E Masi, ED Brenner, F Baluška, F Baluška, F Baluška, F Baluška, F Baluška, F Baluška, F Baluška, HH Felle, HP Bais, HP Bais, J Borghetti, J Fromm, JF Miller, K Birbaum, K Yokawa, K Yokawa, L Chua, L Gao, L Geddes, L Kalmar, LO Chua, M Gagliano, M Gagliano, M Gagliano, M Schlicht, MR DeWeese, N Gizzie, P Gács, PW Barlow, R Bellman, S Battistoni, S Mancuso, S Mancuso, S Steinkellner, SP Kosta, TL Graham, V Demin, V Erokhin, WF Dowling, YP Gunji, YV Pershin   +54 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Pond Eutrophication [PDF]

, 2018
Citation: Burden, M., Guo, Q., Krueger, L., & Young, N. (2018) Pond Eutrophication. Unpublished manuscript, Kansas State University, Manhattan, KS.Kirmser Undergraduate Research Award - Group Category, grand prizeDr.
Burden, Maxwell, Guo, Quanqing, Krueger, Laura, Young, Nicholas   +3 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Conventional Machining of Green Aluminum/ Aluminum Nitride Ceramics [PDF]

, 1994
Author Institution: Department of Industrial Engineering, The University of ToledoCurrent methods for producing ceramic parts rely on finish machining using diamond creep feed grinding or some other non-traditional machining method.
Scheller, W. L., II
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source