Results 81 to 90 of about 8,706,014 (300)

Lost in the Vaso‐Occlusion: A Patient's Abdominal Pain Returns With a Vengeance

open access: yes
Pediatric Blood &Cancer, EarlyView.
Dunia Hatabah   +5 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Prospect Green Map: a community map of environmental, historical, cultural, civic, and recreational sites

open access: yes
A map detailing the sites of interest and importance in the Prospect, NC, and the Robeson County area of North Carolina.
Robeson County Green Map Project
core   +1 more source

Kemang Green Map

open access: yes, 2002
A map of Kemang, in South Jakarta, Indonesia, showcasing natural resources and cultural ...
Green Map Indonesia
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Explicit periodic solution for the threeparabolic problem in the unbounded strip with boundary conditions of Riquier type

open access: yesTechnical Transactions
The subject of the paper is the construction of an explicit periodic solution to the boundary problem for a nonhomogeneous threeparabolic equations of sixth order considered in the unbounded space-time layer with boundary conditions of Riquier type.
Koroński Jan
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Positive bounded solutions for nonlinear polyharmonic problems in the unit ball

open access: yesAnalele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2017
In this paper, we study the existence of positive solutions for the following nonlinear polyharmonic equation (-∆)mu+λf(x, u) = 0 in B; subject to some boundary conditions, where m is a positive integer, λ is a nonnegative constant and B is the unit ball
Mâagli Habib, Zine El Abidine Zagharide
doaj   +1 more source

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