Results 51 to 60 of about 1,432,362 (247)
In response to climate change and international economic crises, which exacerbate the vulnerability of populations in developing countries to various disturbances and shocks, resilience is proposed as a programmatic solution to prevent the deterioration ...
Harouna Derra +1 more
doaj +1 more source
Stranded nations? Transition risks and opportunities towards a clean economy
The transition away from a fossil-fuel powered economy towards a cleaner production system will create winners and losers in the global trade system. We compile a list of ‘brown’ traded products whose use is highly likely to decline if the world is to ...
Pia Andres +3 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Putting the green back in greenbacks: opportunities for a truly green stimulus
Can countries reorient their productive capacity to become more environmentally friendly and inclusive? To investigate this question this paper uses a standard Input-Output modeling framework and data from 141 countries and regions to construct a new ...
Farzad Taheripour +5 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Green growth and sustainable development goals (SDGs) are two strategies to improve the productivity and competitiveness of countries with respect to environmental protection.
Pardo Martínez Clara Inés +1 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Youth inclusion in value chain development: a case of the aquaculture in Nigeria
Many countries in Sub-Saharan Africa (SSA) have made youth inclusion a top priority in their development agendas. This is aimed at overcoming social, technical, and institutional obstacles and providing fair and significant opportunities for the growth ...
Likimyelesh Nigussie +2 more
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

