Results 81 to 90 of about 2,994,761 (283)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Decarbonizing the Industry With Green Hydrogen

Perseverance to reduce global greenhouse gas emissions and backward economic and ecological issues of excessive use of carbon-based fuels is more preponderant than any other environmental- related policies.
Kurt, M., Altaf, C.T., Demirci Sankır, Nurdan, Karagöz, E., Colak, T.O., Demir, O., Sankır, Mehmet   +6 more
core   +1 more source

Urea electrooxidation coupled with energy-saving H2 production using bimetallic sulfide heterojunctions

Electrochemistry Communications
The theoretical electrocatalytic potential for the urea oxidation reaction (UOR) is notably low at 0.37 V, positioning it as a promising alternative to hydrogen evolution reaction for traditional water electrolysis.
Suzhen Bai, Kesheng Cao, Yi Zeng, Zhengshan Tian, Xiangxiang Du, Xingqun Zheng   +5 more
doaj   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

An alkaline electrolyzer having a diaphragm surface coating to enable bubble formation and thus reduce the crossover rates of the product gases

Invention Disclosure
Alkaline electrolyzer technology is widely considered the most mature and cost-effective way of producing green hydrogen, provided the electricity to operate the electrolyzer is generated via renewable energies.
Torsten Berning, Diogo Loureiro Martinho
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Composite zeolite catalysts and catalyst grading technology for high-efficiency hydrocracking of 1-methylnaphthalene to BTX

Fuel Processing Technology
Hydrocracking of polycyclic aromatic hydrocarbons (PAHs) to produce benzene, toluene, and xylene (BTX) represents an effective route for upgrading light cycle oil (LCO).
Zunlong Hu, Denglei Gao, Huanrong Liu, Qingyang Li, Linjie Wang, Xiaofei Zhang, Haodong Xie, Yuhan He, Xiulin Wang, Changjian Liu, Zhijie Wu   +10 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Systematic Analysis of the Hydrogen Value Chain from Production to Utilization

Applied Sciences
Hydrogen produced from renewable sources has the potential to tackle various energy challenges, from allowing cost-effective transportation of renewable energy from production to consumption regions to decarbonizing intensive energy consumption ...
Miguel Simão Coelho, Guilherme Gaspar, Elena Surra, Pedro Jorge Coelho, Ana Filipa Ferreira   +4 more
doaj   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source