Results 91 to 100 of about 1,334,218 (311)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
When and why does it pay to be green? [PDF]
Environmental policy; innovation; Porter hypothesis; environmental regulation; pollution; capital market; green products.
Paul Lanoie, Stefan Ambec
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Mapping the knowledge of green innovation: a systematic literature review [PDF]
Journal of Humanities and Applied Social SciencesPurpose – Green innovations (GI) is an emerging field that presents an opportunity to thrive in the competitive market. Nevertheless, in the field of green innovation, there is no clear and complete picture.
L.R. Rupasinghe +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
The determinants of eco innovation in green supply chains: evidence form an Italian sectoral study [PDF]
In the last years attention has increased to the eco-innovation topic. Empirical studies have demonstrated that innovating firms grow faster, have higher productivity and are more profitable than their less innovative counterparts (Geroski et al., 1993 ...
Fabio Iraldo +2 more
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The level of adoption of green supply chain management and green innovation in Malaysian manufacturing industries [PDF]
, 2018 Recently, corporate environmental practice such as Green Supply Chain Management (GSCM) and green innovation appears as a novel organized environmental practice for manufacturing companies to handle the increasing environmental issues.
Abu Seman, Noor Aslinda +4 more
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Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Climate policy uncertainty, environmental regulation, and corporate green innovation
Frontiers in Environmental ScienceGreen innovation is an important driver for enterprises to realize sustainable development, but there are “double externalities” of environmental protection and knowledge spillovers.
Dan Yi, Jun Hu, Jianlan Yang
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source