Results 141 to 150 of about 40,944 (264)

Dynamics of in-hospital body composition changes in mild and moderately severe acute pancreatitis: trajectories and predictors. [PDF]

Front Nutr
Sun D, Zhou X, Li H, Lin H.
europepmc   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Substantial aircraft contrail formation at low soot emission levels. [PDF]

Nature
Voigt C, Märkl R, Sauer D, Dischl R, Renard C, Seeliger K, Yu F, Kaufmann S, Bräuer T, Jurkat-Witschas T, Le Chenadec G, Moreau J, Requena-Esteban E, Bonne N, Vals M, Roche A, Zelina J, Dörnbrack A, Eirenschmalz L, Heckl C, Horst E, Lichtenstern M, Marsing A, Neumann G, Roiger A, Scheibe M, Stock P, Giez A, Eckel G, Le Clercq P.   +29 more
europepmc   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Metabolic Syndrome Predisposes Ossabaw Minipig Retina to an Early Neurodegenerative Milieu. [PDF]

Cells
Go S, Lim RR, Thomas AE, Mishra PK, Chaurasia SS.   +4 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Metabolic consequences of perinatal bisphenol A and 17α-Ethinylestradiol exposure manifest in circadian alterations of energy homeostasis in adult male mice. [PDF]

Front Endocrinol (Lausanne)
Kalló I, Kádár A, Göblyös B, Vastagh C, Pap DM, Fekete C, Liposits Z.   +6 more
europepmc   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Regulatory impact of intermittent fasting on autophagy in high fat diet induced structural and cognitive brain deteriorations in rats. [PDF]

Sci Rep
Aref M, Hadhod S, Mahran NA, Alqahtani HA, Gadelmawla MHA, Abed Elsalam Elzohier M, Kandeel SA, Ahmed AFA, Hamed A, El-Sayed SM, Elsheikh EH, El-Malkey NF.   +11 more
europepmc   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source