Results 61 to 70 of about 40,944 (264)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Leveraging Lean and Green Supply Chain Practices for Sustainable Supply Chain Performance: The Moderating Role of Environmental Orientation

Engineering Management in Production and Services
This study investigates the impact of lean and green supply chain practices on business process performance and sustainable supply chain performance. The research utilises the resource-based view (RBV) theory to construct a conceptual model wherein lean ...
Aladaileh Mohammad J., Aladayleh Khaled J., Lahuerta-Otero Eva, Cordero-Gutiérrez Rebeca   +3 more
doaj   +1 more source

CI at Scale: Lean, Green, and Fast

2025 IEEE/ACM 47th International Conference on Software Engineering: Software Engineering in Practice (ICSE-SEIP)
Maintaining a "green" mainline branch, where all builds pass successfully, is crucial but challenging in fast-paced, large-scale software development environments, particularly with concurrent code changes in large monorepos. SubmitQueue, a system designed to address these challenges, speculatively executes builds and only lands changes with successful
Dhruva Juloori, Zhongpeng Lin, Matthew Williams, Eddy Shin, Sonal Mahajan   +4 more
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Modelling the interrelationship between factors for adoption of sustainable lean manufacturing: a business case from the Indian automobile industry

International Journal of Sustainable Engineering, 2020
Growth of automobile industry plays a significant role in the Indian Economy. Global warming and increased pollution levels force all countries to revisit their environmental policies towards achieving sustainability.
Naveen Kumar, K. Mathiyazhagan, Deepak Mathivathanan   +2 more
doaj   +1 more source

The Green Lean Amine Machine: Harvesting Electric Power While Capturing Carbon Dioxide from Breath. [PDF]

Adv Sci (Weinh), 2021
Kalkus TJ, Guha A, Scholten PBV, Nagornii D, Coskun A, Ianiro A, Mayer M.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

A Review on Achieving Sustainability in the Petroleum Industry Through the Integration of Lean and Green

Applied Sciences
The petroleum industry has been a key driver in the development of the world economy yet continues to attract increasing criticism due to its negative environmental impact via greenhouse gas emissions, resource inefficiency, and waste.
Felister Dibia, Chinedu Dibia, Hom Nath Dhakal, Oghenovo Okpako, Jovana Radulovic, Augustine Isike   +5 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source