Results 101 to 110 of about 1,994,351 (308)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

The Genesis of the Bowling Green Public Library [PDF]

open access: yes, 2004
A history of library services in Bowling Green, Kentucky, the county seat of Warren County.This article traces the history of the early library movement in Bowling Green and the eventual establishment of a Works Progress Administration library in 1938 ...
Jeffrey, Jonathan
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Helm, Margie May, 1894-1991 (MSS 250) [PDF]

open access: yes, 2009
Finding aid only for Manuscripts Collection 250. Correspondence and business papers related to WKU librarian Margie Helm\u27s role in the establishment of the Bowling Green Public Library, and her involvement in the Kentucky Bookmobile ...
Folklife Archives, Manuscripts &
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Helm, Margie May, 1894-1991 (SC 2439) [PDF]

open access: yes, 2010
Finding aid only for Manuscripts Small Collection 2439. Correspondence, clippings, and miscellaneous items of Margie May Helm, Bowling Green, Kentucky, chiefly related to public library work in Kentucky and ...
Folklife Archives, Manuscripts &
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Electrochemical preparation of polypyrrole-molybdenum disulfide-graphene nanocomposite coating for the determination of phenols

open access: yesTalanta Open
In this work, a nanocomposite of molybdenum disulfide (MoS₂) and graphene (r-GO) was synthesized using hydrothermal method, and was subsequently employed as a dopant to fabricate a hybrid coating of polypyrrole (PPy)-r-GO-MoS₂ via cyclic voltammetry (CV).
Ting Liang   +4 more
doaj   +1 more source

Weeks, Estella T. (SC 670) [PDF]

open access: yes, 2013
Finding aid and scan representative of material in the collection (Click on additional files below) for Manuscripts Small Collection 670. Correspondence of Miss Estella T.
Folklife Archives, Manuscripts &
core   +1 more source

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