Results 71 to 80 of about 5,971,343 (292)

Mass observation / by Mass Observation.

open access: yes, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

G7 Green Gummies France Avis - Green Gummies Commentaires Avantages Prix, acheter

open access: yes, 2023
<p>G7 Plus Gummies France Avis Les « Green Gummies » sont un complément alimentaire conçu pour favoriser la perte de poids. Ces compléments visent à stimuler le métabolisme, à intensifier la combustion des graisses et à optimiser le bien-être ...
G7 Green Gummies
core   +1 more source

SOYBEAN VARIETIES FOR ALTAY AREA AND THEIR CULTIVATION FEATURES

open access: yesЗерновое хозяйство России, 2018
There is a great necessity of a set of highly productive, well-adapted, complementary, economically specific and ecologically differentiated crops and varieties to realize agro climatic potential of West Siberia. Soybean is one of them.
E. R. Shchukis, S. K. Shchukis
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

THE EFFICIENCY OF SAINFOIN BREEDING FOR FODDER AND SEED PRODUCTIVITY

open access: yesЗерновое хозяйство России, 2018
The breeding work on the development of new sainfoin varieties is being constantly carried out, that makes it possible to identify genotypes with high fodder and seed productivity.
S. A. Ignatiev, A. A. Regidin
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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