Results 191 to 200 of about 2,460,304 (285)

Microstructural Features Linking White Matter and Mathematics in Adolescence. [PDF]

ASN Neuro
Geeraert BL, Kunimoto K, Lebel RM, Lebel C.   +3 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Stand-alone graph-based lung airway labeling with quantitative validations. [PDF]

Med Phys
Chen H, Modiri A, Sawant A.
europepmc   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Detection of <i>Solanum betaceum Cav</i> fruit maturity using YOLO11-based deep learning. [PDF]

Front Plant Sci
Quiñones Huatangari L, Vásquez Pérez HV, Valqui-Valqui L, Palomino Ojeda JM, Saravia D, Bardales Escalante W, Silva G, Chavez-Jalk A, Cruz Caro O, Valqui L.   +9 more
europepmc   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Letter: S.D. Green to Ida M. Tarbell, April 3, 1924

, 1924
Green, S.D.
core   +1 more source

Quantification of Peripheral Blur in Ultra-Widefield Fundus Imaging Following Diffractive Multifocal Intraocular Lens Implantation. [PDF]

J Clin Med
Kim SM, Bang SP, Lee SB.
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Green space exposure predicts manic episodes in bipolar disorder: one year longitudinal analysis using smartphone-derived GPS data. [PDF]

Npj Ment Health Res
Guth M, Bittendorf CA, Krug C, Mühlbauer E, Severus WE, Bauer M, Reichert M, Ludwig VM, Ebner-Priemer UW.   +8 more
europepmc   +1 more source