Results 221 to 230 of about 2,460,304 (285)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Differential effects of free viewing and goal-directed search on visual attention: An eye-tracking study. [PDF]

PLoS One
Yue C, Chi J, Liu J, Wang Y, Zhang C, Cao M.   +5 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Dynamic albumin-to-RDW trajectories for time-dependent risk stratification in acute brain injury. [PDF]

Front Nutr
Wang J, Xu MM, Peng Z, Li WJ, Duan ML, Hang CH, Zhao PL.   +6 more
europepmc   +1 more source

Robust quantification of ICG fluorescence perfusion in neonatal bowel surgery via deep point tracking. [PDF]

Int J Comput Assist Radiol Surg
Mao Z, Composto A, Neville J, Cirelli C, Stoyanov D, Giuliani S, Bano S.   +6 more
europepmc   +1 more source

Recyclable HFIP-mediated, atom-economical cycloisomerisation of biaryl ynamides for the sustainable synthesis of polycyclic (hetero)aromatics. [PDF]

RSC Adv
Satyanarayana ANV, Nayak BK, Sai Keerthana H, Naresh A, Chatterjee T.   +4 more
europepmc   +1 more source

A combination of unenhanced CT-derived features predicts renal parenchymal involvement of immunoglobulin G4-related disease. [PDF]

Eur Radiol Exp
Inui J, Amaike H, Kanda M, Yama N, Takahashi H, Hatakenaka M.   +5 more
europepmc   +1 more source

Urban tree canopy fragmentation and child mortality in low- and middle-income countries. [PDF]

Proc Natl Acad Sci U S A
Chi D, Richards D, Manoli G, Yang J, Ji JS, Zhang Y, Lin B, Hahs A, Liu C, Zhu Y, Qiu Y, Wang J, Burlando P, Fatichi S, Tan PY.   +14 more
europepmc   +1 more source

Enhancing detection of polygenic adaptation: a comparative study of machine learning and statistical approaches using simulated evolve-and-resequence data. [PDF]

BMC Genomics
Caliendo C, Gerber S, Pfenninger M.
europepmc   +1 more source