Results 161 to 170 of about 462,069 (303)

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Multifunction Green Open Space for Environmental Education

, 2019
With huge pressures from a rapidly growing population, Jakarta suffers from an increasingly low Environmental Quality Index (IKLH). In 2016 and 2017 it was the only province in Indonesia with the IKLH index “alert” according to the Ministry of ...
Vivanti, D. (Diana), Dewi, R. I. (Riyawati), Sya, A. (Ahman)   +2 more
core  

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Exploring how hospital based green spaces support stroke rehabilitation: A mixed methods multiple case study protocol. [PDF]

PLoS One
Burton LJ, Crocker T, Coventry P, Hill L, Walsh A, Myers E, Speed M, Akanuwe J, Forster A.   +8 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Are green spaces healthier in spring? Examining seasonal variations in the association between urban green spaces and emotional well-being in Wuhan, China. [PDF]

Front Public Health
Xu Z, Zhang Z, Li B, Wu Y, Jia Y.
europepmc   +1 more source

Disaster-resilient cities and open green spaces

The rapid and unplanned urbanization processes worldwide intensify the adverse impacts of physical, social, and environmental factors, rendering cities more vulnerable. Balancing the numerous economic, environmental, administrative, and social elements within cities and reducing their vulnerability to become resilient against stress and shocks have ...
Demiroğlu, Demet, Karadağ, Aybike Ayfer, Kurtaslan, Banu Öztürk, Ermiyagil, Selen Abbasoğlu   +3 more
openaire   +1 more source

Migration- refugees and open-green spaces: Kilis case/Turkey

, 2019
Today most important migration movement is taking place in Syria due to the civil war. Most of the Syrian asylum-seekers have sought refuge in Turkey. The migration has led to many problems in the areas such as physical, social, cultural and economical in the country. One of these areas is urban open and green spaces.
Demiroğlu, Demet, Çoban, Ayşe, Karadağ, A.A., Cengiz, A.E.   +3 more
openaire   +3 more sources