Results 111 to 120 of about 500,274 (264)

Urban Spatial Naturalness Degree in the Planning of Ultra-High-Density Cities: The Case of Urban Green Open Spaces in Macau

Buildings
This study deeply examines the livable environment in high-density cities like Macau, focusing on urban green spaces. The study introduces the “urban spatial naturalness degree” indicator, exploring its application with urban population growth and green ...
Jitai Li, Fan Lin, Hongcan Cui, Shuai Yang, Yile Chen   +4 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Evaluasi Ruang Terbuka Hijau di Kecamatan Sleman Kabupaten Sleman

Planta Tropika: Jurnal Agrosains, 2015
The development of urban area gives negative impact on the environmental aspects, such as the decreasing of areas for green open space. Therefore, it is necessary to implement the research about evaluation of green open space.
Vinda Catur Nugroho
doaj  

Can urban forests alleviate eye strain? Evidence from eye-tracking metrics

Trees, Forests and People
With the surge in digital screen use, eye strain has become a growing public health concern. While urban forests are known to support psychological and physiological restoration, their capacity to alleviate eye strain remains underexplored.
Yihao Lu, Hui Liu, Bingqing Liu, Han Diao, Jianan Wang   +4 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Green Infrastructure Planning for Cluster Green Open Spaces in Sentul City

IOP Conference Series: Earth and Environmental Science
Abstract Sustainability has emerged as a global agenda that has developed rapidly over the past few decades, encompassing environmental, economic, and social dimensions. Sentul City, a planned satellite town in Bogor Regency, adopts green development principles through the implementation of green city attributes ...
Nuri Hasanah, Bambang Sulistyantara
openaire   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

IMPLIKASI KEBIJAKAN RUANG TERBUKA HIJAU DALAM PENATAAN RUANG DI JAWA BARAT

Fiat Justisia, 2015
Green Open Space (RTH) diminishing lead to the emergence of insecurity and social diseases and influence the improvement of micro-climate, air pollution, floods, and various other negative environmental impacts.
nadia astriani
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source