Results 131 to 140 of about 199,661 (307)

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Sustainable public procurement in public higher education institutions: basic principles and the need for their implementation

Економіка, управління та адміністрування
Today, when the whole humanity must confront the global environmental challenges facing society, it is necessary to introduce new technologies in all areas of activity that will help ensure the preservation of the planet’s ecology.
O.A. Pylypchuk
doaj   +1 more source

PUBLIC PROCUREMENT AS TOOL OF ENVIRONMENTAL POLICY [PDF]

Correlating private and social interests represents a continuous challenge for environmental policy. Traditional implementation tools proved to be not enough for accomplishing the objectives required by the protection of natural systems.
Florina BRAN, Ildiko IOAN
core  

Organic school food policies are supportive for healthier eating behaviours – results from an observational study in Danish schools [PDF]

, 2010
Purpose – The purpose of this study was to examine whether organic food intervention strategies in Danish school meal systems can support the development of healthier eating patterns among pupils.
Chen, He, Løes, Anne-Kristin, Mikkelsen, Bent Egberg   +2 more
core  

Hyperviscous Diabetic Bone Marrow Niche Impairs BMSCs Osteogenesis via TRPV2‐Mediated Cytoskeletal‐Nuclear Mechanotransduction

Advanced Science, EarlyView.
Diabetic bone marrow exhibits pathological ECM hyperviscosity that activates TRPV2‐mediated Ca2⁺ influx, leading to perinuclear F‐actin disassembly, nuclear deformation, and chromatin condensation. This cytoskeletal‐nuclear decoupling suppresses osteogenic differentiation of BMSCs.
Yao Wen, Xinhui Zheng, Jieliu Li, Minyu He, Dongqi Fan, Xingyu Zhu, Qiming Zhai, Liangjing Xin, Tao Chen   +8 more
wiley   +1 more source

Alternatives to PPPs: positive action for in-house services [PDF]

, 2008
The paper reviews empirical examples of policies and approaches for developing public services through public sector provision and direct employment, in the context of EU ...
Hall, David
core  

Stochastic Nanoscale Biophysical Cues as a Basis for the Induction of Glioblastoma‐Like Transcriptional Programs in Astrocytes

Advanced Science, EarlyView.
Stochastic nanoscale physical cues induce glioblastoma (GBM)‐associated transcriptional traits in naïve astrocytes leading to spontaneous formation of spheroids. Cells within spheroids express activated‐MMP2 and a differential gene expression pattern involving P53 and NOTCH3, providing evidence for a role for changes in brain topography, as observed in
Laurent Starck, Tobias Butelmann, Sabrina Hogan, Melika Sarem, Bernd Heimrich, Ritwick Sawarkar, Marie‐Françoise Ritz, Gregor Hutter, V. Prasad Shastri   +8 more
wiley   +1 more source

Critical Factors for Green Public Procurement: The Case of Greece

Logistics
Background: Green Public Procurement (GPP) is a sector that has been growing in recent years through policies encouraged by the European Union. In the Greek public sector, the respective National Action Plan (NAP), which sets specific targets for GPP ...
Varvara S. Orfanidou, Dimitrios J. Dimitriou, Nikolaos P. Rachaniotis, Giannis T. Tsoulfas   +3 more
doaj   +1 more source

Relevance of Social, Economic, and Environmental Impacts on Residents’ Satisfaction with the Public Administration of Tourism [PDF]

, 2019
Those in charge of tourism destinations face the need to create tourism development models compatible with the essence of the localities that they manage.
Revilla Camacho, María Ángeles, Rodríguez Rad, Carlos J., Sánchez del Río Vázquez, María Elena   +2 more
core  

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source