Results 31 to 40 of about 1,963,691 (292)

Procuring green energy in the construction sector : perspectives on inter-connecting green procurement and impact assessment

open access: yes
The construction sector consumes significant quantities of energy, thus contributing to almost 50 percent of the global greenhouse gas emissions. The construction sector must consider a renewable component to their energy procurement as a means to ...
Mörtberg, Ulla,   +3 more
core   +4 more sources

Evaluation framework for green procurement in road construction [PDF]

open access: yes, 2014
Purpose\ud \ud Most barriers and enablers of sustainable projects are related to procurement. This study proposes a framework for evaluating green procurement practices throughout the lifecycle of road construction projects and demonstrates its ...
Lehtiranta, Liisa   +10 more
core   +2 more sources

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Determinants for Green Procurement Practices in Public Procurement Management in Tanzania

open access: yesBusiness Review
This study explores the determinants of green procurement practices in public procurement management in Tanzania. Using a mixed-methods approach, the research applied descriptive and multiple linear regression analyses to data from 200 public ...
Yohana Arsen Rutaba
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

Increasing IA effectiveness by green procurement

open access: yes, 2010
The aim of this paper is to contribute towards the knowledge of increasing environmental performance of the construction industry by focusing on strengthening the links between project planning and project implementation.
Balfors, Berit,   +2 more
core   +3 more sources

Region Specific miRNA–mRNA Networks in Gray and White Matter Lesions of Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Multiple sclerosis (MS) is a neurodegenerative demyelinating disease of the central nervous system. This study aimed to identify micro‐RNA (miRNA)–mRNA regulatory networks underlying region‐specific molecular mechanisms in white matter and gray matter lesions in progressive MS.
Adya Sapra   +5 more
wiley   +1 more source

The Role of Green Public Procurement in the Implementation of Sustainable Development. City of Łódź Case Study

open access: yesBarometr Regionalny, 2019
The article concerns the practical use of green public procurement to implement sustainable development. The use of this type of instrument in the investment activity of the city in the years 2007–2017 is presented on the example of the City of Łódź ...
Małgorzata Burchard-Dziubińska   +1 more
doaj   +1 more source

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