Nanometer Layer Coating to Lactose Particles for Optimization of Dexamethasone Pulmonary Delivery
Nanometer layer coating (NLC) was investigated and its mechanism illustrated by advanced characterization techniques. The effects and application for the inhalation of dexamethasone (DEX) were demonstrated through in vitro and in vivo evaluation. This approach increased DEX bioavailability and enabled the dose to be reduced to 1/30 of the intravenous ...
Qin Nie +11 more
wiley +1 more source
A Novel Method of Improving the Mechanical Properties of Propellant Using Energetic Thermoplastic Elastomers with Bonding Groups. [PDF]
Sun S +5 more
europepmc +1 more source
Developing Soft Interconnected Microchannel Network for 2D Skin‐Like Actuator
A soft interconnected network of microchannels is proposed to develop new pneumatic actuators for future bio‐inspired soft robots. Simultaneous stimulation of this network generates regional asymmetric strains in walls of microchannels whose interaction across the entire surface leads to bending curvatures in multidimensions.
John Noee +4 more
wiley +1 more source
Climate Change and the Switch from Pressurised Metered-Dose Inhalers to Dry Powder Inhalers: A Proportionate Balancing of Risk and Reward? [PDF]
Dissanayake S, Suggett J, Kaplan A.
europepmc +1 more source
Morphological anisotropy directs the in vivo transport under physiological flow and clearance of silica nanocarriers. Increasing anisotropy reduces cellular uptake, suppresses hepatic and splenic sequestration, and prolongs systemic circulation by steering particles toward the central flow core.
Xiaofei Li +11 more
wiley +1 more source
Trends in low global warming potential inhaler prescribing: A UK-wide cohort comparison from 2018-2024. [PDF]
Barry SM +7 more
europepmc +1 more source
A Robotic Testing Platform for Pipelined Discovery of Resilient Dielectric Elastomer Actuators
This work introduces a robotic testing platform enabling high‐throughput, multi‐parameter lifetime mapping of linear dielectric elastomer actuators (DEAs). By integrating programmable high‐voltage control and automated electromechanical measurements, the system identifies material and operating conditions that double actuator lifetime.
Ang (Leo) Li +10 more
wiley +1 more source
Effect of Metastable Intermolecular Composites on the Thermal Decomposition of Glycidyl Azide Polymer Energetic Thermoplastic Elastomer. [PDF]
Sang C, Luo Y.
europepmc +1 more source
Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue
This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg +19 more
wiley +1 more source
Ammonia (NH3) Production from the Thermal Decomposition of Hydroxylammonium Nitrate (HAN) as a Green Energetic Source for Clean Space. [PDF]
Souagh A +4 more
europepmc +1 more source

