Results 41 to 50 of about 7,751,164 (248)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Carolina Planning Vol. 30.2: Green Building, Green Planning [PDF]

, 2005
Green Building: What is it and Why Should Planners Care?; Flawed Process, Flawed Results, and a Potential Solution; The Cleveland Eco-Village Case Study: Connecting Green Affordable Housing and City Planning; Building Value with Building Science: High ...
Department of City and Regional Planning
core   +1 more source

Green Map Flushing Meadow Queens NY

, 2005
A map of Flushing Meadows Corona Park in Queens, NY, site of two world fairs (1939 and 1964) currently home to a number of recreation facilities and green space.
Green Map System (Firm)
core   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Close-To-Nature Heuristic Design Principles for Future Urban Green Infrastructure

Urban Planning, 2021
The global nature-climate crisis along with a fundamental shift in world population towards cities and towns has sharpened the focus on the role of urban green infrastructure. Green infrastructure has the potential to deliver cost-effective, nature-based
Saruhan Mosler, Peter Hobson
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Changes in Green Space Use During a COVID-19 Lockdown Are Associated With Both Individual and Green Space Characteristics

, 2022
Mobility restrictions imposed during the COVID-19 pandemic present a useful study system for understanding the temporal and spatial patterns of green space use.
Berdejo-Espinola, V, Rhodes, JR, Zahnow, R, Suárez-Castro, AF, Fuller, RA   +4 more
core   +1 more source

Strategic Planning of Surabaya City Government in Managing Public Green Open Space (A Study at the Surabaya City Sanitation and Green Open Space Agency)

Jurnal Pembangunan dan Alam Lestari, 2020
Public Green Open Space is one of the important components in managing cities in order to realize the mandate of Law Number 26 of 2007 concerning Spatial Planning, namely the proportion of Public Green Open Space in city areas of at least 20% of the ...
Oktarizka Reviandani, Soesilo Zauhar, Endah Setyowati   +2 more
doaj  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Green space and physical activity: an observational study using Health Survey for England data. [PDF]

, 2012
Past studies have suggested that a link between health outcomes and green space is due to increased levels of physical activity of individuals living in areas with more green space.
Townsend, Nicholas, Mytton, OT, Foster, C, Rutter, Harry, Townsend, N, Foster, Charlie, Townsend, Nick, Foster, Charles, Rutter, H, Mytton, Oliver T   +9 more
core   +1 more source