Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Retracted: Green Supply Chain Management and Its Impact on Economic-Environmental Performance: Evidence from Asian Countries. [PDF]
J Environ Public Health, 2023 Environmental And Public Health JO.
europepmc +1 more source
The implementation of Green Supply Chain Management (GSCM) and Environmental Management System (EMS) practices and its impact on Market Competitiveness during Covid-19 [PDF]
Environ Sci Pollut Res Int, 2023 Das G +5 more
europepmc +2 more sources
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
AI in supply chain: Techniques, applications, real-world cases and benefits under SCOR framework [PDF]
This article focuses on practical perspectives of Artificial Intelligence (AI) applications in Supply Chain Management by exploring commonly used AI techniques, use cases and benefits of applying AI in Supply Chain Management with real-world examples ...
Briš, Petr, Pham Hoang, Bao
core
Going green: Impact of green supply chain management practices on sustainability performance. [PDF]
Front Psychol, 2022 Ahmad A, Ikram A, Rehan MF, Ahmad A.
europepmc +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Green Supply Chain Optimization Based on BP Neural Network. [PDF]
Front Neurorobot, 2022 Wang H.
europepmc +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source