Results 41 to 50 of about 113,527 (217)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The interplay between green supply chain management practices and firm performance: does green technological innovation and institutional pressure matter? [PDF]

Journal of Responsible Production and Consumption
PurposeThis study aims to investigate the impact of green supply chain management practices on firm performance and the intervening roles of green technological innovation and institutional pressures in this relationship.Design/methodology/approachThis ...
Alexander Otchere Fianko, Daniel Etse, Meshach Awuah-Gyawu, Darlington Bright Yao Adanfo   +3 more
doaj   +1 more source

Dual-Channel Green Supply Chain Decision-Making and Coordination considering CSR and Consumer Green Preferences

Discrete Dynamics in Nature and Society, 2021
With the rapid development of the Internet and changes in consumer buying habits, many manufacturers are increasingly relying on online channels to sell their products as opposed to traditional retail channels.
Xiaochun Chen, Rui Zhang, Bo Lv
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Green Supply Chain: Studi Keterkaitannya dengan Kinerja Lingkungan dan Kinerja Finansial

Jurnal Manajemen Dan Kewirausahaan, 2018
This study aims to analyze the linkage of green supply chain management, environmental performance and financial performance. The research population are all restaurants in Malang with propotional random sampling as sampling technique.
Ayu Rohdayatin, Pudjo Sugito, Krisnawuri Handayani   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Supply Chain Digitalization, Green Supply Chain, Supply Chain Resilience Toward Competitiveness and MSMEs Performance

Jurnal Aplikasi Manajemen
MSMEs that previously only relied on human resources are now forced to keep up with the times by utilizing IT in every process, from raw material procurement, production processes to distribution processes in order to remain competitive in facing a ...
Zainurrafiqi Zainurrafiqi, Gazali Gazali
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Game theory analysis of operational decision-making in green supply chain: The impact of consumer preferences [PDF]

SHS Web of Conferences
In the current global context of increasing emphasis on sustainable development, high carbon emissions and resource waste in traditional supply chains have become critical factors affecting supply chain efficiency.
Shi Ruomeng
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source