Results 51 to 60 of about 13,106,545 (241)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Green supply chain management practices and performance [PDF]

Industrial Management & Data Systems, 2013
PurposeThe purpose of this study is to examine the deployment of pro‐active and re‐active practices in the implementation of green supply chain management (GSCM) and analyze their impact on environmental, economic, and intangible performance by considering business strategy as organizational focus.Design/methodology/approachData were collected from a ...
Tritos Laosirihongthong, Dotun Adebanjo, Keah Choon Tan   +2 more
openaire   +1 more source

Blockchain Technology and Trust in Supply Chain Management: A Literature Review and Research Agenda

, 2021
Applying blockchain technology for information sharing in supply chain is driven by many factors, but developing trust is one of the most proposed. However, trust is a multidimensional, intangible concept without an agreed-upon definition.
Norrman, Andreas, Batwa, Abbas, Norrman, Andreas,, Lund University., Batwa, Abbas,, Abbas Batwa, Andreas Norrman   +6 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Supply Chain Risk Governance: Towards a Conceptual Multi-Level Framework [PDF]

, 2020
The coronavirus pandemic (COVID-19) is currently putting high pressure on most countries’ critical infrastructures (not only health care), creating huge uncertainties in supply and demand, and disrupting global supply chains.
Norrman, Andreas, Ahlqvist, Victoria, Jahre, Marianne, Ahlqvist, Victoria,, Norrman, Andreas,, Lund University., Jahre, Marianne,, Marianne Jahre, Victoria Ahlqvist, Andreas Norrman   +9 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Synergizing TQM, JIT, and Green Supply Chain Practices: Strategic Insights for Enhanced Environmental Performance

Logistics
Background: This study examined the role of total quality management, just-in-time, and green supply chain management practices to improve environmental performance. Methods: Data from 207 manufacturing industry respondents from a developing economy were
Aamir Rashid, Rizwana Rasheed, Noor Aina Amirah   +2 more
doaj   +1 more source

Carbon emission reduction effects and mechanisms of green supply chains policies from a stability perspective [PDF]

Ziyuan Kexue
[Objective] With the ongoing deepening of green supply chain management practices, it is important to clarify the relationship between such practices and corporate carbon emission reductions, and to uncover the moderating effect of supply chain stability,
GAO Wenjing, HAO Chunrui, SUN Jiayi, LIANG Xin, JIANG Jin
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source