Results 151 to 160 of about 1,012,476 (308)

Contrasting Coordination- and Debromination-Driven Dimerization of Dibenzo[c,g]carbazole Derivatives on Ag(111) Visualized by STM

Crystals
Here, we report a comparative scanning tunneling microscopy study of two brominated dibenzo[c,g]carbazole derivatives on Ag(111): 5,9-dibromo-7H-dibenzo[c,g]carbazole (DBC) and 5,9,7-tribromo-7-(4-bromobutyl)-7H-dibenzo[c,g]carbazole (BrBu-DBC).
Yan Li, Xiang Zhang, Maoyun Lang, Shenwei Chen, Peng Hu   +4 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

Molecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini, Maria Caterina Mione   +1 more
wiley   +1 more source

Green Chemistry Education: Recent Developments Green chemical processing ;, vol. 4./ Mark Anthony Benvenuto and Larry Kolopajlo.

, 2019
In English.Includes bibliographical references and index.Kolopajlo, Larry / Benvenuto, Mark -- Noce, Anthony M. -- Berger, Michael / Karod, Madeline / Goldfarb, Jillian L. -- Sadraei, S. Iraj / Onge, Brent St / Trant, John F.
Krikke James., Pothoof Justin., Kolopajlo Lawrence H.,, Berger Michael., Kohn Craig., Onge Brent S., Sliwinski Ben D., Ruprecht Michal., Benvenuto (Mark Anthony),, Sosnowski Ben M., Fitzgerald Polly R., Wathen Steven P., Goldfarb Jillian L., Kosmas Steven., Kovacs Dalila., Ause Robert., Mack Kristina., Noce Anthony., Patel Jay M., Sadraei S. Iraj., Trant John F., Karod Madeline., Mill Theodore., Tebes-Stevens Caroline.   +23 more
core  

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Origanum vulgare mediated green synthesis of biocompatible gold nanoparticles simultaneously possessing plasmonic, antioxidant and antimicrobial properties

, 2018
Daniela Benedec,1,* Ilioara Oniga,1,* Flavia Cuibus,1 Bogdan Sevastre,2 Gabriela Stiufiuc,3 Mihaela Duma,4 Daniela Hanganu,1 Cristian Iacovita,1 Rares Stiufiuc,1,5 Constantin Mihai Lucaciu1 1Faculty of Pharmacy, “Iuliu Haţieganu” University ...
Lucaciu CM, Stiufiuc R, Oniga I, Stiufiuc G, Hanganu D, Iacovita C, Sevastre B, Benedec D, Cuibus F, Duma M   +9 more
core  

Green Synthesis of Nanoparticles

5th INTERNATIONAL CONFERENCE ON BIOLOGICAL RESEARCH AND APPLIED SCIENCE
Nanotechnology is a novel and developing field of study with a wide range of applications. It involves the synthesis and application of materials called nanoparticles which are having dimensions of 1-100nm. Nowadays, the production of nanoparticles (NPs) is accomplished by a broad range of physico–chemical methods.
openaire   +3 more sources

Synergistic enhancement of electrochemical alcohol oxidation by combining NiV-layered double hydroxide with an aminoxyl radical

Nature Communications
Electrochemical alcohol oxidation (EAO) represents an effective method for the production of high-value carbonyl products. However, its industrial viability is hindered by suboptimal efficiency stemming from low reaction rates.
Suiqin Li, Shibin Wang, Yuhang Wang, Jiahui He, Kai Li, James B. Gerken, Shannon S. Stahl, Xing Zhong, Jianguo Wang   +8 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source