Advanced Science, EarlyView.BCR sequencing and subclone analysis correlated immunoglobulin (Ig) chain loss in dysfunctional hybridomas with disrupted monoclonal antibody homeostasis. Proteomics‐guided CRISPR/Cas9 editing revealed that the unfolded protein response (UPR) regulates aberrant Ig synthesis.
Rubing Zou +9 more
wiley +1 more source
Evaluation and heterogeneity of the green total factor productivity of Shandong Province, China: a super-SBM and GML analysis. [PDF]
Sci RepMa M, Yang Y, Ma Y, Wang Z.
europepmc +1 more source
Advanced Science, EarlyView.By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang +27 more
wiley +1 more source
Research on the impact and mechanism of digital economy on China's urban green total factor productivity. [PDF]
Sci RepLiu L, Pang Y, Liu B.
europepmc +1 more source
Green Total Factor Productivity and Its Saving Effect on the Green Factor in China's Strategic Minerals Industry from 1998-2017. [PDF]
Int J Environ Res Public Health, 2022 Jin Y, Yu L, Wang Y.
europepmc +1 more source
A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time
Advanced Science, EarlyView.This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li +15 more
wiley +1 more source
The impact of carbon emissions trading on green total factor productivity based on evidence from a quasi-natural experiment. [PDF]
Sci RepHu H.
europepmc +1 more source
EGR Proteins Mediate Interferon‐Independent Anti‐HSV‐1 Responses Through Viral and Host Targets
Advanced Science, EarlyView.Early antiviral responses are typically mediated by interferons. However, during HSV‐1 infection, host early growth response (Egr) genes, which are not interferon‐stimulated genes, are quickly induced by viral protein ICP0. EGR proteins, in turn, suppress viral lytic infection by activating viral latency‐associated (LAT) and host immune regulatory ...
Shuaishuai Wang +4 more
wiley +1 more source
Realizing the Improvement of Green Total Factor Productivity of the Marine Economy-New Evidence from China's Coastal Areas. [PDF]
Int J Environ Res Public Health, 2022 Ren W, Chen Y.
europepmc +1 more source
A perspective of scale differences for studying the green total factor productivity of Chinese laying hens. [PDF]
Sci Rep, 2022 Zhong S, Chen X, Li J, Jiang S.
europepmc +1 more source