Results 101 to 110 of about 1,317,398 (262)

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Microbial interactions as the key to understanding and controlling environmental spread of antibiotic resistance genes

open access: yesnpj Antimicrobials and Resistance
Beyond abiotic factors, microbial interactions are critical yet understudied regulators of environmental antibiotic resistance gene (ARG) spread, whose neglect hinders control efforts.
Haining Huang   +11 more
doaj   +1 more source

Insights into community profiles, environmental influence, and assembly mechanisms of oyster-associated bacteriome from Yueqing Bay, China via absolute quantitation by metabarcoding

open access: yesFrontiers in Microbiology
BackgroundOyster populations create new habitats, maintain productivity, improve water quality by removing excess nutrients in coastal environments, and provide a source of animal protein. More importantly, their associated bacteriome is likely a primary
Huai Lin   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Asymmetric charge-polarization tailoring active hydrogen transfer for selective photoreduction CO2 to CH4

open access: yesNature Communications
Photocatalytic reduction of CO2 to natural gas using water vapor is a promising strategy for carbon recycling and renewable energy storage. However, the selectivity of current catalysts still remains a big challenge.
Chenxu Yin   +6 more
doaj   +1 more source

Microbial Community and Metabolic Pathways in Anaerobic Digestion of Organic Solid Wastes: Progress, Challenges and Prospects

open access: yesFermentation
Anaerobic digestion (AD) is a sustainable and widely adopted technology for the treatment of organic solid wastes (OSWs). However, AD efficiency varies significantly across different substrates, primarily due to differences in the microbial community and
Jiachang Cao   +5 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Advances in PFAS Degradation by Iron-Based Materials and Underlying Mechanisms

open access: yes能源环境保护
Per- and polyfluoroalkyl substances (PFAS) are of significant environmental concern due to their exceptional chemical stability and bioaccumulation potential, posing serious threats to ecosystems and human health.
Yujie Huang   +7 more
doaj   +1 more source

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