Results 41 to 50 of about 15,740 (221)

Modeling the ACMG/AMP Variant Classification Guidelines as a Bayesian Classification Framework

open access: yesGenetics in Medicine, 2018
We evaluated the American College of Medical Genetics and Genomics/Association for Molecular Pathology (ACMG/AMP) variant pathogenicity guidelines for internal consistency and compatibility with Bayesian statistical reasoning.
S. Tavtigian   +6 more
semanticscholar   +1 more source

AI Alignment Versus AI Ethical Treatment: 10 Challenges

open access: yesAnalytic Philosophy, EarlyView.
ABSTRACT A morally acceptable course of AI development should avoid two dangers: creating unaligned AI systems that pose a threat to humanity and mistreating AI systems that merit moral consideration in their own right. This paper argues these two dangers interact and that if we create AI systems that merit moral consideration, simultaneously avoiding ...
Adam Bradley, Bradford Saad
wiley   +1 more source

Diseño de una estrategia de infusión de midazolam ajustada al modelo farmacocinético de Greenblatt

open access: yesRevista Cubana de Anestesiología y Reanimación, 2014
Introducción: los sistemas de administración automática de fármacos, constituyen herramientas de investigación con un alto impacto en la práctica de la anestesiología. Objetivo: exponer la metodología que permitió el ajuste de los cálculos para el diseño
Jorge Rosa Díaz   +1 more
doaj  

Preliminary study documents variable accuracy and inclusion among biology instructor gender/sex definitions

open access: yesNatural Sciences Education, Volume 55, Issue 2, December 2026.
Abstract Society generally presents sex inaccurately as a binary variable based on one or few trait(s), causing myriad issues, including the pursuit of reductionist biology experiments, the creation of laws that limit the rights of women, people with queer genders, and intersex folks, and greater student endorsement of gender stereotypes in ...
Emily P. Driessen   +4 more
wiley   +1 more source

Discovery of a Potent and Selective MAO‐B Inhibitor From a Donepezil‐Linked Chalcone Library With Promising Antiparkinsonian Activity

open access: yesDrug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A focused library of 19 donepezil‐linked chalcones (DLCs) was efficiently synthesised through microwave‐assisted Claisen‐Schmidt condensation and subsequently profiled for their inhibitory activities against cholinesterases (AChE and BuChE) as well as monoamine oxidases (MAO‐A and MAO‐B).
Azize Kirac‐Aydin   +11 more
wiley   +1 more source

Piotroski, Graham and Greenblatt: an Empirical Approach to Value Investing in the Brazilian Stock Market

open access: yesBBR: Brazilian Business Review, 2022
In this paper, multifactor asset pricing models are used to assess and compare the performance - through the analysis of Jensen’s alpha - of three equity portfolios constructed according to the value investing strategies proposed by Joseph Piotroski ...
Carlos Henrique Souza Domingues   +3 more
doaj   +1 more source

Occupational resilience: Scoping review of conceptualisations and applications in contexts of adversity

open access: yesAustralian Occupational Therapy Journal, Volume 73, Issue 4, August 2026.
Abstract Introduction Occupational resilience has emerged as a construct that links the capacity to face adversity with the role of meaningful occupations in the adaptation and recovery of individuals, groups, and communities. However, its definition, theoretical frameworks, and applications remain heterogeneous and partial.
Gema Puig‐Esteve, Rodolfo Morrison
wiley   +1 more source

Fake Shakespeare

open access: yesJournal of Early Modern Studies, 2016
The essay examines the relationship between Shakespeare and Fletcher’s lost play The History of Cardenio and Theobald’s 1727 adaptation Double Falsehood, and various twentieth-first century attempts (by Greenblatt and Mee, Doran and Álamo, and Gary ...
Gary Taylor
doaj   +1 more source

Simplified Transition and Turbulence Modeling for Oscillatory Pipe Flows

open access: yesEnergies, 2021
One-dimensional unsteady Reynolds-averaged Navier–Stokes computations were performed for oscillatory transitional and turbulent pipe flows and the results were validated against existing experimental data for a wide variety of oscillatory Reynolds and ...
Alexander Shapiro   +2 more
doaj   +1 more source

Dedication – Susan L Greenblatt [PDF]

open access: yesJournal of Physics: Conference Series, 2011
Figure 1. Susan in May, 1994 This volume is dedicated to the memory of Susan L Greenblatt, the wife of Steven L Guberman. Susan attended 6 of the 8 dissociative recombination (DR) meetings. Her advice and wise counsel played a vital role in the organization of several of these meetings. The fifth meeting in Chicago in 2001 was her idea and it would not
openaire   +1 more source

Home - About - Disclaimer - Privacy