Results 61 to 70 of about 699,371 (334)

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Birds of a central São Paulo woodlot: 1. Censuses 1982-2000

Brazilian Journal of Biology, 2002
Some 263 birds were recorded near and in a 230-ha patch of semideciduous forest in cane fields of central São Paulo, Brazil. Subtracting 67 open-area species, 22 of marshes or creeks, 10 vagrants and 12 recorded later, 152 forest and border species were ...
WILLIS E. O., ONIKI Y.
doaj  

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

DEVELOPMENT OF INTERACTIVE CONTENT IN WEBSITE LEARNING MEDIA TO ADDRESS STUDENT MISCONCEPTIONS ABOUT THE GREENHOUSE EFFECT

Jurnal Pendidikan Matematika dan IPA
This study addresses the pressing need to improve students' comprehension of the greenhouse effect by leveraging innovative website-based Augmented Reality (AR) learning media.
Syva Lestiyani Dewi, Dede Trie Kurniawan, Rendi Restiana Sukardi   +2 more
doaj   +1 more source

Temporal variability of soil CO2 emission after conventional and reduced tillage described by an exponential decay in time model Variabilidade temporal da emissão de CO2 do solo após preparo convencional e reduzido descrito por modelo exponencial decrescente no tempo

Engenharia Agrícola, 2010
To study Assessing the impact of tillage practices on soil carbon losses dependents it is necessary to describe the temporal variability of soil CO2 emission after tillage.
Luis G Teixeira, Afonso Lopes, Newton La Scala Jr   +2 more
doaj   +1 more source

Climate Change Policy as Economic Stimulus: Evidence and Opportunities From the States [PDF]

, 2008
Using data from twenty states with climate change mitigation policies, creates an aggregate model to estimate their potential economic stimulus effect, as well as cost savings and reductions in fossil fuel consumption and greenhouse gas ...

core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Pareto Optimality in the Extraction of Fossil Fuels and the Greenhouse Effect: A Note [PDF]

This note generalizes the Solow-Stiglitz efficiency condition for natural resources to the problem of fossil fuel extraction with a greenhouse effect. The generalized optimality condition suggests that the greenhouse effect implies overextraction in the ...
Hans-Werner Sinn
core   +3 more sources

A project-based system for including farmers in the EU ETS [PDF]

, 2011
Farmers in the EU do not trade greenhouse gases under the Kyoto agreement. This is an empirical puzzle because agriculture is a significant contributor of greenhouse gases (GHG) in the EU and may harvest private net gains from trade. Furthermore, the US
Brandt, Urs Steiner, Svendsen, Gert Tinggaard   +1 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source