Results 151 to 160 of about 3,620,058 (390)

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

Advanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu, Xiumei Zhao, Maolin Zang, Huiyang Yuan, Xin Qin, Xiaofeng Li, Shuo Zhao, Ruirong Tan, Keqiang Yan, Li Liu, Yidong Fan, Ning Zhang, Benkang Shi, Bo Han, Shouzhen Chen   +14 more
wiley   +1 more source

Greenhouse Gas Economics and Computable General Equilibrium [PDF]

, 1998
Hans W. Gottinger
openalex   +1 more source

Microbiome Single Cell Atlases Generated with a Commercial Instrument

Advanced Science, EarlyView.
Single cell sequencing is valuable for dissecting complex systems and uncovering unique features in individual cell types. However, tools for single cell microbial analysis are limited. Easily Accessible Single microbe sequencing (EASi‐seq), which adapts a commercially available single cell platform for efficient sequencing of single microbial genomes ...
Xiangpeng Li, Linfeng Xu, Benjamin Demaree, Cecilia Noecker, Jordan E. Bisanz, Daniel W. Weisgerber, Cyrus Modavi, Peter J. Turnbaugh, Adam R. Abate   +8 more
wiley   +1 more source

Global greenhouse gas reconciliation 2022

Earth System Science Data
Abstract. In this study, we provide an update on the methodology and data used by Deng et al. (2022) to compare the national greenhouse gas inventories (NGHGIs) and atmospheric inversion model ensembles contributed by international research teams coordinated by the Global Carbon Project.
Z. Deng, Z. Deng, Z. Deng, P. Ciais, L. Hu, A. Martinez, M. Saunois, R. L. Thompson, K. Tibrewal, W. Peters, W. Peters, B. Byrne, G. Grassi, P. I. Palmer, P. I. Palmer, I. T. Luijkx, Z. Liu, J. Liu, J. Liu, X. Fang, T. Wang, H. Tian, K. Tanaka, K. Tanaka, A. Bastos, S. Sitch, B. Poulter, C. Albergel, A. Tsuruta, S. Maksyutov, R. Janardanan, Y. Niwa, Y. Niwa, B. Zheng, B. Zheng, J. Thanwerdas, D. Belikov, A. Segers, F. Chevallier   +38 more
openaire   +5 more sources

An Injectable BMP‐2‐Releasing Porous Hydrogel Regulating the Paracrine Effects of ADSCs Promotes Tendon‐to‐Bone Healing in Rotator Cuff Repair

Advanced Science, EarlyView.
This study designs an injectable porous hydrogel (HMs/MBs/ADSCs) integrating hollow microspheres for sustained BMP‐2 release to enhance adipose‐derived stem cells' paracrine effect. It accelerates tendon‐bone healing in rat rotator cuff injuries via spatiotemporal regulation: early AMPK‐mediated mitochondrial protection and late TGF‐β/Smad2/3‐driven ...
Meijuan Yuan, Xiaomei Dai, Yuxia Yang, Shuai Liu, Ziyi Xu, Liang Wang, Junli Shi, Wenkang Liu, Jian Yang, Dianwei Liu, Hang Yao, Wenyong Fei   +11 more
wiley   +1 more source

JA‐Mediated Regulation of Amino Acid Homeostasis Adjusts Metabolic Flux and Enhances Spider Mite Tolerance via the SlJAZ8‐SlWRKY57‐SlAVT6s Module in Tomato

Advanced Science, EarlyView.
This study elucidates a novel SlJAZ8‐SlWRKY57‐SlAVT6A/SlAVT6B module that effectively channels metabolic flux from primary to secondary metabolism, impacting plant growth, development, and resistance. Two novel vacuolar amino acid exporters, SlAVT6A and SlAVT6B, fine‐tunes trichomes, terpenes, and gibberellins, bolstering spider mite resistance.
Yingchen Hao, Xiaolong Wang, Langchen Guo, Lijun Xiang, Enxi Luo, Peng Cao, Penghui Liu, Yue Zhong, Chun Li, Jun Lai, Jun Yang, Shouchuang Wang   +11 more
wiley   +1 more source

Climate change and greenhouse gases [PDF]

, 1999

openalex   +1 more source

The Shared Socioeconomic Pathways and their energy, land use, and greenhouse gas emissions implications: An overview

, 2017
K. Riahi, D. P. Vuuren, E. Kriegler, J. Edmonds, B. O’Neill, S. Fujimori, N. Bauer, K. Calvin, R. Dellink, Oliver Fricko, W. Lutz, A. Popp, J. Cuaresma, S. Kc, Marian Leimbach, Leiwen Jiang, T. Kram, Shilpa Rao, J. Emmerling, K. Ebi, T. Hasegawa, P. Havlík, Florian Humpenöder, L. Silva, Steven J. Smith, E. Stehfest, V. Bosetti, J. Eom, D. Gernaat, T. Masui, J. Rogelj, J. Strefler, L. Drouet, V. Krey, Gunnar Luderer, M. Harmsen, Kiyoshi Takahashi, Lavinia Baumstark, J. Doelman, M. Kainuma, Z. Klimont, G. Marangoni, H. Lotze-Campen, M. Obersteiner, A. Tabeau, M. Tavoni   +45 more
semanticscholar   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Carbon emissions and sequestration in forests: Case studies from seven developing countries. Volume 2, Greenhouse gas emissions from deforestration in the Brazilian Amazon

, 1992
Willy Makundi, Jayant Sathaye, Philip M. Fearnside   +2 more
openalex   +2 more sources