Results 201 to 210 of about 54,439 (256)

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Determinants of undergraduate bioscience engagement: Validating attendance barriers and classroom spatial behaviour across institutions

open access: yesFEBS Open Bio, EarlyView.
Student engagement extends beyond simple attendance. Across 891 bioscience students from three universities, attendance behaviour was associated mainly with structural influences, whereas classroom spatial behaviour reflected affective and sensory factors.
Nigel Page   +4 more
wiley   +1 more source
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Green transistors to green architectures

Proceedings of the 2009 ACM/IEEE international symposium on Low power electronics and design, 2009
This talk will highlight different generations of energy-efficient device architectures that enable aggressive supply voltage reduction. First, we will discuss the impact of the introduction of a new gate stack with high-K dielectrics and the use of multigate control structures. Next, we will show that incorporation of ultra-high mobility compound (III-
Suman Datta, Vijaykrishnan Narayanan
openaire   +2 more sources

Green solvents for green technologies

Journal of Biotechnology, 2017
Within ‘green economy’ approach, growing area of research in the development of green technologies is devoted to designing new, more environmentally friendly solvents. As a promising alternative to traditional organic solvents deep eutectic solvents (DESs) have been dramatically expanding in popularity last few years as a new generation of designer ...
Bubalo Kovačić, Marina   +6 more
openaire   +5 more sources

How Green is ‘Green’ Energy?

Trends in Ecology & Evolution, 2017
Renewable energy is an important piece of the puzzle in meeting growing energy demands and mitigating climate change, but the potentially adverse effects of such technologies are often overlooked. Given that climate and ecology are inextricably linked, assessing the effects of energy technologies requires one to consider their full suite of global ...
Gibson, Luke   +2 more
openaire   +3 more sources

Green Preference, Green Investment

2023
Based on Alibaba’s renowned “green” initiative, the Ant Forest program, we develop a novel measure to reveal an individual investor’s nonpecuniary green preference and link it to an individual’s investment actions. We present compelling evidence that supports nonfinancial incentives for investing in green mutual funds while divesting from “brown” funds.
Zhenyu Gao, Yan Luo, Shu Tian, Hao Yang
openaire   +2 more sources

GREEN MARKETING FOR GREEN TOURISM

New Trends in Tourism and Hospitality Management : Proceedings of the 21st Biennial International Congress Tourism & Hospitality Industry 2012, 2012
Mass tourism is a thing of the past for the tourist countries that wish to develop their tourism in a well considered way. For this reason tourist countries, including the Republic of Croatia, need to develop a new model of tourism that should be based also on so-called alternative tourism.
Ham, Marija, Meler, Marcel
openaire   +2 more sources

Green thoughts in a green shade

Photosynthesis Research, 1990
The author gives an autobiographical sketch of his path to chlorophyll research, and describes some results. The discussion is largely focused on long wavelength forms of chlorophyll and how they might be generated by self-assembly. Dimers or oligomers, (Chl)n, result from coordination interactions between the central magnesium atom of one macrocycle ...
openaire   +2 more sources

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