Results 51 to 60 of about 5,319 (217)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Evaluation of Insect Farming Residue (Frass) as a Phosphate Fertilizer Within the Context of the Circular Economy

Agronomy
Phosphorus (P) stock scarcity is driving the need to develop alternatives to mineral fertilizers. The growing production of insects for high-protein feed results in significant amounts of residues (frass), which can be used as fertilizers.
Juan Nieto-Cantero, Miguel A. Romero-Gil, Gina P. Suárez-Cáceres, Antonio Delgado, Víctor M. Fernández-Cabanás   +4 more
doaj   +1 more source

Urban Land-Cover Dynamics in Arid China Based on High-Resolution Urban Land Mapping Products

Remote Sensing, 2017
Rapid urbanization has occurred in northwestern China, threatening the sustainability of its fragile dryland ecosystems. A lack of precise urban land-cover information has limited our understanding on the urbanization in the dryland.
Tao Pan, Dengsheng Lu, Chi Zhang, Xi Chen, Hua Shao, Wenhui Kuang, Wenfeng Chi, Zhengjia Liu, Guoming Du, Liangzhong Cao   +9 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Irkutsk as a Potential Growth Point of Greening Processes in Russia

Prace Komisji Geografii Przemysłu Polskiego Towarzystwa Geograficznego, 2020
Greening has no alternatives in contemporary world. Yet in Russia another process is taking place – the weakening of environmental consciousness in the conditions of economic backwardness. Our hypothesis is that the only hope is connected with some local
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

"The Greens" and "Green Fire" [PDF]

Pacific Conservation Biology, 1997
"The Greens", written by Bob Brown and Peter Singer introduces the Greens to a wide audience. Both authors were Green candidates for the Australian Senate at the time of writing. Bob Brown is one of the founders of the Australian Greens. As director of the Tasmanian Wilderness Society, he led the campaign that saved the Franklin River from impoundment ...
openaire   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Analysis of ecological environment differences and attribution between China and India

Ecological Indicators
Vegetation greening not only offers climate benefits but also enhances residents' well-being in urban areas. China and India lead the world in terms of global greening.
Jiawen Zhao, Liqun Sun, Chan Zhou
doaj   +1 more source