Results 71 to 80 of about 4,341,666 (299)

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

The Multicriteria Assessment of the Green Growth in the Context of the European Union’s Green Deal

www.amfiteatrueconomic.ro, 2022
The article deals with the issue of assessment of the green growth in context of the Green Deal in the European Union Countries. Because this issue leads to the decision problem which has typical the properties of multi-criteria decision making (MCDM), the Analytical Hierarchy Process (AHP) method, including the sensitivity analysis, was used as a ...
openaire   +4 more sources

Comprehensive assessment of greenness of ICP-OES methods for determination of metals

Green Analytical Chemistry
This paper evaluates the greenness of Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES) methods for determination metal and metalloid.
Aesha Bhalodia, Sonal Desai
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

A Green HPLC Approach to Florfenicol Analysis in Pig Urine

Pharmaceuticals
Florfenicol (FF) is a broad-spectrum antibiotic used to treat gastrointestinal and respiratory infections in domestic animals. Considering FF’s rapid elimination via urine after drug treatment, its use increases concerns about environmental contamination.
Ksenija Šandor, Eleonora Perak Junaković, Svjetlana Terzić, Irena Žarković, Anja Vujnović, Dominika Fajdić, Mirta Pehnec, Sonja Sinković, Irena Ćaleta, Miroslav Andrišić   +9 more
doaj   +1 more source

A New Green Index as an Overall Quantitative Green Performance Indicator of a Facility

Chemical Engineering Transactions, 2015
In assessing the greenness of a facility, a few green performance indicators and assessment tools such as the Building Research Establishment Environmental Assessment Method (BREEAM), the Leadership in Energy and Environmental Design (LEED), and Green ...
M.A. Mustapha, Z.A. Manan, S.R. Wan Alwi
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

The grey-green divide: multi-temporal analysis of greenness across 10,000 urban centres derived from the Global Human Settlement Layer (GHSL)

International Journal of Digital Earth, 2020
The presence of green spaces within city centres has been recognized as a valuable component of the city landscape. Vegetation provides a variety of benefits including energy saving, improved air quality, reduced noise pollution, decreased ambient ...
Christina Corbane, Pesaresi Martino, Politis Panagiotis, Florczyk J. Aneta, Melchiorri Michele, Freire Sergio, Schiavina Marcello, Ehrlich Daniele, Naumann Gustavo, Kemper Thomas   +9 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source