SNF8, a member of the ESCRT-II complex, interacts with TRPC6 and enhances its channel activity
Background Transient receptor potential canonical (TRPC) channels are non-selective cation channels involved in receptor-mediated calcium signaling in diverse cells and tissues.
Carrasquillo Robert +5 more
doaj +1 more source
Metabolic profiling of human plasma and urine in chronic kidney disease by hydrophilic interaction liquid chromatography coupled with time-of-flight mass spectrometry : a pilot study [PDF]
A typical characteristic of chronic kidney disease (CKD) is the progressive loss in renal function over a period of months or years with the concomitant accumulation of uremic retention solutes in the body.
Boelaert, Jente +5 more
core +1 more source
Jonathan Littell, Les Bienveillantes
Główną postacią Les Bienveillantes jest Hauptsturmführer Max Aue, doktora prawa, inspektor SD, wywiadu SS, człowiek przesiąknięty kulturą humanizmu, władający starożytną greką, jak jego pisarza, Max Thomas, postać autentyczna.
Michel Laffite
doaj +1 more source
Recurring Lower Abdominal Pain and Fever as Initial Presentation of Adult Onset Still’s Disease in the Absence of Arthralgia and Other System Involvement [PDF]
A 34 year-old Afro-Caribbean female presented with recurring episodes of fever and lower abdominal pain over a period of two months not improving despite courses of antibiotics for possible recurrent urinary tract infections.
Rajaiah, Nithyananda +2 more
core +3 more sources
Randomized Clinical Trial Design to Assess Abatacept in Resistant Nephrotic Syndrome
Treatment-resistant nephrotic syndrome is a rare form of glomerular disease that occurs in children and adults. No Food and Drug Administration−approved treatments consistently achieve remission of proteinuria and preservation of kidney function.
Howard Trachtman +11 more
doaj +1 more source
Meksykańska literatura prekolumbijska a konotacje genologiczno-retoryczne Europy
Artykuł odnosi się do tzw. miejsc wspólnych dwu kultur z zakresu genologii porównawczej i antropologii generatywnej. Skupiono się na trzech zagadnieniach o szczególnym znaczeniu dla obu cywilizacji: motywie narodzin i gatunku utworów urodzinowych ...
Beata Gaj
doaj +1 more source
Mitochondria play a crucial role in tubular injury in diabetic kidney disease (DKD). MitoQ is a mitochondria-targeted antioxidant that exerts protective effects in diabetic mice, but the mechanism underlying these effects is not clear.
Li Xiao +15 more
doaj +1 more source
The slav reception of Gregory of Nyssa’s works: an overview of early slavonic translations [PDF]
Although a lot has been written about the "translatio" of Byzantine Christianity in the mediaeval Slavia orthodoxa, advancing a critical assessment of the Slav reception of the Greek Fathers remains a precarious undertaking.
Sels, Lara
core +1 more source
Molecular Determinants of the Sensitivity to Gq/11-Phospholipase C-dependent Gating, Gd3+ Potentiation, and Ca2+ Permeability in the Transient Receptor Potential Canonical Type 5 (TRPC5) Channel [PDF]
Transient receptor potential canonical type 5 (TRPC5) is a Ca2+-permeable cation channel that is highly expressed in the brain and is implicated in motor coordination, innate fear behavior, and seizure genesis.
Chakraborty, Saikat Chakrabort +6 more
core +1 more source
GABA receptors, widely expressed in the retina, play a key role in lateral inhibition and synaptic regulation. Emerging evidence links their dysregulation to retinal diseases such as diabetic retinopathy, retinitis pigmentosa, glaucoma, and age‐related macular degeneration.
Alan E. Medina Arellano +5 more
wiley +1 more source

