Results 41 to 50 of about 546 (115)

Greka Nowego Testamentu - recenzja [PDF]

open access: yes, 2013
Recenzja: Andrzej Piwowar, Greka Nowego Testamentu. Gramatyka, Kielce 2010, 590 s. (Biblioteka „Verbum Vitae” t. 1)
Czarnuch, Monika
core  

From Neurotransmission to Retinal Pathophysiology: Unraveling the Role of GABA Receptors in Retinal Disease Progression

open access: yesJournal of Neurochemistry, Volume 169, Issue 8, August 2025.
GABA receptors, widely expressed in the retina, play a key role in lateral inhibition and synaptic regulation. Emerging evidence links their dysregulation to retinal diseases such as diabetic retinopathy, retinitis pigmentosa, glaucoma, and age‐related macular degeneration.
Alan E. Medina Arellano   +5 more
wiley   +1 more source

FALCON systematically interrogates FFA biology and identifies new mediators of lipotoxicity

open access: yes, 2023
Cellular vulnerability to free fatty acids (FFA) is implicated in the modern epidemic of obesity and its sequelae, including type 2 diabetes (T2D).
Coraor Fried, Juliana Mathea
core   +4 more sources

Randomized Clinical Trial Design to Assess Abatacept in Resistant Nephrotic Syndrome

open access: yesKidney International Reports, 2018
Treatment-resistant nephrotic syndrome is a rare form of glomerular disease that occurs in children and adults. No Food and Drug Administration−approved treatments consistently achieve remission of proteinuria and preservation of kidney function.
Howard Trachtman   +11 more
doaj   +1 more source

Calcium, TRPC channels, and regulation of the actin cytoskeleton in podocytes: towards a future of targeted therapies [PDF]

open access: yes, 2016
With more than 6,000 new pediatric patients with treatment-resistant nephrotic syndrome in the US each year alone, the unmet need for novel, podocyte-specific therapies is substantial.
Wieder, Nicolas, Greka, Anna
core   +1 more source

Potent, selective, and subunit‐dependent activation of TRPC5 channels by a xanthine derivative

open access: yesBritish Journal of Pharmacology, Volume 176, Issue 20, Page 3924-3938, October 2019., 2019
Background and Purpose The TRPC1, TRPC4, and TRPC5 proteins form homotetrameric or heterotetrameric, calcium‐permeable cation channels that are involved in various disease states. Recent research has yielded specific and potent xanthine‐based TRPC1/4/5 inhibitors.
Aisling Minard   +10 more
wiley   +1 more source

The mitochondria-targeted antioxidant MitoQ ameliorated tubular injury mediated by mitophagy in diabetic kidney disease via Nrf2/PINK1

open access: yesRedox Biology, 2017
Mitochondria play a crucial role in tubular injury in diabetic kidney disease (DKD). MitoQ is a mitochondria-targeted antioxidant that exerts protective effects in diabetic mice, but the mechanism underlying these effects is not clear.
Li Xiao   +15 more
doaj   +1 more source

Cryo‐Imaging and Software Platform for Analysis of Molecular MR Imaging of Micrometastases

open access: yesInternational Journal of Biomedical Imaging, Volume 2018, Issue 1, 2018., 2018
We created and evaluated a preclinical, multimodality imaging, and software platform to assess molecular imaging of small metastases. This included experimental methods (e.g., GFP‐labeled tumor and high resolution multispectral cryo‐imaging), nonrigid image registration, and interactive visualization of imaging agent targeting.
Mohammed Q. Qutaish   +10 more
wiley   +1 more source

O tożsamości chrześcijańskiej Rozmowa z Księdzem Arcybiskupem Józefem Życińskim

open access: yesHoryzonty Wychowania, 2017
KRYSTYNA ABLEWICZ, WIT PASIERBEK SJ: Każdy człowiek posiada przedrozumienie własnej tożsamości. Jak Ksiądz Arcybiskup rozumie pojęcie tożsamości przynależnej każdej osobie na mocy jej godności i tożsamości chrześcijańskiej? ARCYBISKUP JÓZEF ŻYCIŃSKI: Dla
Krystyna Ablewicz, Wit Pasierbek
doaj  

Immersed in Motion: A Narrative Review on Physical Activity Intensity and Mental Health Benefits in Blue Spaces

open access: yesUrban Science
Blue spaces (BS) are increasingly recognized for their potential to support mental health and well-being, yet the specific role of physical activity (PA) within these environments remains underexplored. This narrative review aimed to synthesize empirical
Argyro Anna Kanelli   +2 more
doaj   +1 more source

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