Results 151 to 160 of about 848,748 (280)

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Multiplexed Profiling of Individual Extracellular Vesicles Reveals Lung Cancer‐Associated Protein Signatures

Advanced Science, EarlyView.
Cygnus (Cyclic‐imaging gateway to nanovesicles underlying signature) integrates multiplexed single‐EV protein imaging with a practical analysis workflow to examine EV phenotypes at vesicle, subpopulation, and sample scales. ABSTRACT Lung cancer is frequently diagnosed after curative treatment windows have narrowed, creating a need for minimally ...
Mi Hyeon Cho, Yein Chung, Yoonjeong Choi, Baekdong Cha, Jayeon Song, Nuri Oh, Ala Jo, Thomas S. C. Ng, Hyunho Kim, Hyun‐Kyung Woo, Chang Hyun Kim, Cesar M. Castro, Miles A. Miller, Hakho Lee   +13 more
wiley   +1 more source

Accumulation of CO2 limits energy gain in freely diving grey seals. [PDF]

J Exp Biol
Bønnelycke ES, Kershaw JL, Hastie GD, Sparling C, Balfour S, Milne R, Moss SEW, Wright PFC, McKnight JC.   +8 more
europepmc   +1 more source

Grey Systems Analysis

This open access book is the 2nd edition involving the update on data, methods and models of Grey Systems. It covers up-to-date theoretical and applied advances in grey systems from across the world, and vividly presents the reader with the overall ...
Liu, Sifeng
core   +1 more source

Advances in Se Wide‐Bandgap Photovoltaics and TexSe1‐x SWIR Photodiodes

Advanced Science, EarlyView.
In this review, fundamental properties and current challenges in Se photovoltaics (PVs) for tandem and indoor PVs and TexSe1‐x alloys for short wave infrared photodiodes are discussed. A case is made for the practicality of elemental chalcogenide optoelectronics, and a pathway toward resolving the key challenges in these respective technologies is ...
Adam D. Alfieri, Deep Jariwala
wiley   +1 more source

Habitat fidelity of adult grey seals over multiple years in a changing marine ecosystem. [PDF]

Mov Ecol
Nowak BVR, Bowen WD, Lidgard DC, den Heyer CE.   +3 more
europepmc   +1 more source

Forensic microbiology reveals that Neisseria animaloris infections in harbour porpoises follow traumatic injuries by grey seals. [PDF]

Sci Rep, 2019
Foster G, Whatmore AM, Dagleish MP, Malnick H, Gilbert MJ, Begeman L, Macgregor SK, Davison NJ, Roest HJ, Jepson P, Howie F, Muchowski J, Brownlow AC, Wagenaar JA, Kik MJL, Deaville R, Doeschate MTIT, Barley J, Hunter L, IJsseldijk LL.   +19 more
europepmc   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Molecular Mechanisms Underlying Response to Influenza in Grey Seals (Halichoerus grypus), a Potential Wild Reservoir. [PDF]

Mol Ecol
McCosker CM, Unal E, Gigliotti A, Puryear WB, Runstadler JA, Murray KT, King BL, Cammen KM.   +7 more
europepmc   +1 more source

Dental pulp exposure, periapical inflammation and suppurative osteomyelitis of the jaws in juvenile Baltic grey seals (Halichoerus grypus grypus) from the late 19th century. [PDF]

PLoS One, 2019
Kierdorf U, Olsen MT, Kahle P, Ludolphy C, Kierdorf H.   +4 more
europepmc   +1 more source