Results 51 to 60 of about 21,213 (304)

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Small signal modeling and stability analysis of multi-VSCs for grid-forming converters under low impedance grid

电力工程技术
The grid-forming converter has voltage source characteristics，providing damping and frequency support to high-impedance weak grids，and demonstrates good stability. However，instability may occur under low impedance grids.
Yongkang CHEN, Yunhui HUANG, Zheng FANG, Dong WANG, Jinrui TANG, Keliang ZHOU   +5 more
doaj   +1 more source

Key Parameter Estimation Method for Frequency Modulation of Receiving- End Grid-Forming Converters Considering Damping Control [PDF]

Dianli jianshe
[Objective] Driven by the “dual carbon” goals， the installed capacity of new energy sources has grown rapidly， and the system inertia characteristics are evolving from physical inertia to virtual inertia.
YAN Xiangwu, XU Yue, ZHANG Hui, QU Yue, LI Bohan, WANG Haoming, JIA Jiaoxin
doaj   +1 more source

Validation Aspects for Grid-Forming Converters Based on System Characteristics and Inertia Impact

Energies, 2023
Grid-forming converters are considered a key technology for electrical grids with a high share of renewable energy. However, there is a lack of a general, robust and verifiable definition of what constitutes this behaviour. Therefore, this paper presents
Julian Struwe, Holger Wrede, Hendrik Vennegeerts   +2 more
doaj   +1 more source

Distributed Apportioning in a Power Network for providing Demand Response Services

, 2017
Greater penetration of Distributed Energy Resources (DERs) in power networks requires coordination strategies that allow for self-adjustment of contributions in a network of DERs, owing to variability in generation and demand.
Attree, Sandeep, Patel, Sourav, Prakash, Mangal, Salapaka, Murti V., Talukdar, Saurav   +4 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Grid‐forming requirements based on stability assessment for 100% converter‐based Irish power system

IET Renewable Power Generation, 2022
The fault response of a 100% converter‐based system can be significantly different to that of a synchronous generator‐based system, considering the lower capacity headroom, but flexible control capability, of power electronic converters.
Xianxian Zhao, Priyanko Guha Thakurta, Damian Flynn   +2 more
doaj   +1 more source

Smart microgrids and virtual power plants in a hierarchical control structure [PDF]

, 2011
In order to achieve a coordinated integration of distributed energy resources in the electrical network, an aggregation of these resources is required. Microgrids and virtual power plants (VPPs) address this issue.
De Kooning, Jeroen, Meersman, Bart, Vandevelde, Lieven, Vandoorn, Tine, Zwaenepoel, Brecht   +4 more
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

A novel fault analysis method considering control states for MMC grid-forming system with renewable energy generation

International Journal of Electrical Power & Energy Systems
This paper analyzes the fault equivalent models of grid-following and grid-forming converters under various fault conditions. A novel fault calculation method for MMC-HVDC grid-forming systems integrated with 100% renewable energy generation is proposed.
Bohao Zhou, Jiawei He, Bin Li, Ye Li, Yan Li, Runbin Cao   +5 more
doaj   +1 more source