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Advanced Materials, EarlyView.A hierarchically structured metal–organic framework (eMIL) is shown to host the complete six‐enzyme biosynthesis pathway for the anti‐cancer pigment violacein, reshaping reaction dynamics and multiplying in vitro yields. eMIL nanoreactors deliver this reconstituted bacterial multi‐protein system into mammalian cells, where cell‐derived substrates and ...
Ainur Sharip +12 more
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Hippocampus, 2008
AbstractThe medial entorhinal cortex (EC) is a part of the neural network for the representation of self‐location in the rat. The key cell type of this system is the grid cell, whose multiple firing fields span the environment in a remarkably regular triangular or hexagonal pattern.
Marianne Fyhn +2 more
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AbstractThe medial entorhinal cortex (EC) is a part of the neural network for the representation of self‐location in the rat. The key cell type of this system is the grid cell, whose multiple firing fields span the environment in a remarkably regular triangular or hexagonal pattern.
Marianne Fyhn +2 more
exaly +5 more sources
Annual Review of Neuroscience, 2016
The medial entorhinal cortex (MEC) creates a neural representation of space through a set of functionally dedicated cell types: grid cells, border cells, head direction cells, and speed cells. Grid cells, the most abundant functional cell type in the MEC, have hexagonally arranged firing fields that tile the surface of the environment.
David C. Rowland +3 more
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The medial entorhinal cortex (MEC) creates a neural representation of space through a set of functionally dedicated cell types: grid cells, border cells, head direction cells, and speed cells. Grid cells, the most abundant functional cell type in the MEC, have hexagonally arranged firing fields that tile the surface of the environment.
David C. Rowland +3 more
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Grid cells in pre- and parasubiculum
Nature Neuroscience, 2010Allocentric space is mapped by a widespread brain circuit of functionally specialized cell types located in interconnected subregions of the hippocampal-parahippocampal cortices. Little is known about the neural architectures required to express this variety of firing patterns.
Boccara, Charlotte N. +6 more
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Grid cells in an inhibitory network
Nature Neuroscience, 2014Grid cells have been proposed to reflect competitive interactions in inhibitory neural networks. Experimental results obtained using optogenetics to identify spikes emitted specifically by parvalbumin interneurons now constrain the mechanisms by which such networks could give rise to grid cells.
Yasser, Roudi, Edvard I, Moser
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Computational Mathematics and Modeling, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ardelyan, N. V. +2 more
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zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ardelyan, N. V. +2 more
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Navigating with distorted grid cells
The 2018 Conference on Artificial Life, 2018Grid cells in the hippocampal formation are a valuable system to study both for neuroscientists and for neural network researchers, as these neurons present both a window into higher-level cognitiv...
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Nature Reviews Neuroscience, 2019
Grid cells in the rat medial entorhinal cortex distort their firing patterns local to a reward in the environment.
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Grid cells in the rat medial entorhinal cortex distort their firing patterns local to a reward in the environment.
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A hexagonal Fourier model of grid cells
Hippocampus, 2018AbstractGrid cells in rat medial entorhinal cortex are widely thought to play a major role in spatial behavior. However, the exact computational role of the population of grid cells is not known. Here we provide a descriptive model, which nonetheless considers biologically feasible mechanisms, whereby the grid cells are viewed as a two‐dimensional ...
Ulises Rodríguez‐Domínguez +1 more
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The transformation from grid cells to place cells is robust to noise in the grid pattern.
Hippocampus, 2015Spatial navigation in rodents has been attributed to place-selective cells in the hippocampus and entorhinal cortex. However, there is currently no consensus on the neural mechanisms that generate the place-selective activity in hippocampal place cells or entorhinal grid cells.
Amir H, Azizi +2 more
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