Results 211 to 220 of about 359,372 (263)

ECMSim: A high-performance interactive web application for real-time spatiotemporal simulation of cardiac ECM signaling and diffusion. [PDF]

Matrix Biol Plus
Hays H, Richardson WJ.
europepmc   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

Direct numerical simulation of three-dimensional Kolmogorov flow for turbulence model development. [PDF]

Sci Data
Andrea Kovács K, Balogh M, Kristóf G.
europepmc   +1 more source

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Author Correction: Malaria trends in Ethiopian highlands track the 2000 'slowdown' in global warming. [PDF]

Nat Commun
Rodó X, Martinez PP, Siraj A, Pascual M.   +3 more
europepmc   +1 more source

Membrane Fusion‐Mediated Cytosolic Delivery of Threose Nucleic Acids via Homotypic Nanoparticles Overcomes Drug Resistance in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
This study introduces a biomimetic “nanofusion” platform that integrates the biostability of threose nucleic acids (TNA) with homotypic cell‐membrane cloaking to combat drug‐resistant TNBC. By leveraging a non‐canonical membrane‐fusion pathway for direct cytosolic delivery, the platform bypasses endosomal sequestration. To achieve potent AKT2 silencing
Wei Zheng, Tristan Juin Han Chang, Xinchao Li, Zhongqi Zhou, Chung Tin, Kenward Vong, Pierre Karam, Pik Kwan Lo   +7 more
wiley   +1 more source

geneSCOPE: gene spatial co-occurrence of pairwise expression. [PDF]

Brief Bioinform
Zhang S, Saeki K, Haeno H.
europepmc   +1 more source

From FAIR to CURE: guidelines for computational models of biological systems. [PDF]

NPJ Syst Biol Appl
Sauro HM, Agmon E, Blinov ML, Gennari JH, Hellerstein JL, Heydarabadipour A, Jardine BE, May E, Nickerson DP, Smith LP, Bader GD, Bergmann FT, Boyle PM, Dräger A, Faeder JR, Feng S, Freire J, Fröhlich F, Glazier JA, Gorochowski TE, Helikar T, Hermjakob H, Hoops S, Hunter P, Imoukhuede PI, Keating SM, König M, Laubenbacher R, Loew LM, Lopez CF, Lytton WW, Malik-Sheriff RS, McCulloch A, Mendes P, Mulugeta L, Myers CJ, Myers JG, Niarakis A, Niekerk DDV, Olivier BG, Patrie AA, Quardokus EM, Radde N, Rohwer JM, Sahle S, Schaff JC, Schreiber F, Sego TJ, Shin J, Snoep JL, Vadigepalli R, Wiley HS, Waltemath D, Moraru II.   +53 more
europepmc   +1 more source

MOrbVis: Browser-Based Molecular Orbital Visualization with WebGPU-Accelerated On-the-Fly Evaluation. [PDF]

ACS Omega
Ito Y, Tsuji S, Nakano K, Kasagi A.
europepmc   +1 more source

Protocol for development of a reporting guideline (TRIPOD-Code) for code repositories associated with diagnostic and prognostic prediction model studies. [PDF]

Diagn Progn Res
Pollard T, Sounack T, Gao CA, Celi LA, Lindvall C, Lee H, Lee HC, Moons KGM, Collins GS.   +8 more
europepmc   +1 more source