Results 51 to 60 of about 154,734 (260)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

A Case Study on Distributed Energy Resources and Energy-Storage Systems in a Virtual Power Plant Concept: Economic Aspects

Energies, 2019
This paper analyzes the technical and economic possibilities of integrating distributed energy resources (DERs) and energy-storage systems (ESSs) into a virtual power plant (VPP) and operating them as a single power plant.
Tomasz Sikorski, Michał Jasiński, Edyta Ropuszyńska-Surma, Magdalena Węglarz, Dominika Kaczorowska, Paweł Kostyła, Zbigniew Leonowicz, Robert Lis, Jacek Rezmer, Wilhelm Rojewski, Marian Sobierajski, Jarosław Szymańda, Daniel Bejmert, Przemysław Janik   +13 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Analysis of Wind Generator Operations under Unbalanced Voltage Dips in the Light of the Spanish Grid Code

Energies, 2011
Operation of doubly fed induction generators subjected to transient unbalanced voltage dips is analyzed in this article to verify the fulfillment of the Spanish grid code.
Joaquín Montañana-Romeu, Vicente León-Martínez   +1 more
doaj   +1 more source

Smart Sag Detection and Reactive Current Injection Control for a PV Microgrid under Voltage Faults

Energies, 2023
Low-power photovoltaic distributed generators are increasing rapidly in number by the grids of the modern era, but they also bring up the concern of grid stability.
Muhammad Affan Khan, Jaehong Kim
doaj   +1 more source

Maximally Recoverable Codes for Grid-like Topologies [PDF]

Proceedings of the Twenty-Eighth Annual ACM-SIAM Symposium on Discrete Algorithms, 2017
The explosion in the volumes of data being stored online has resulted in distributed storage systems transitioning to erasure coding based schemes. Yet, the codes being deployed in practice are fairly short. In this work, we address what we view as the main coding theoretic barrier to deploying longer codes in storage: at large lengths, failures are ...
Parikshit Gopalan, Guangda Hu, Swastik Kopparty, Shubhangi Saraf, Carol Wang, Sergey Yekhanin   +5 more
openaire   +2 more sources

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

A multidimensional grid-adaptive relativistic magnetofluid code [PDF]

Computer Physics Communications, 2008
A robust second order, shock-capturing numerical scheme for multi-dimensional special relativistic magnetohydrodynamics on computational domains with adaptive mesh refinement is presented. The base solver is a total variation diminishing Lax-Friedrichs scheme in a finite volume setting and is combined with a diffusive approach for controlling magnetic ...
Bart van der Holst, Rony Keppens, Zakaria Meliani   +2 more
openaire   +3 more sources

Characterization of Defect Distribution in an Additively Manufactured AlSi10Mg as a Function of Processing Parameters and Correlations with Extreme Value Statistics

Advanced Engineering Materials, EarlyView.
Predicting extreme defects in additive manufacturing remains a key challenge limiting its structural reliability. This study proposes a statistical framework that integrates Extreme Value Theory with advanced process indicators to explore defect–process relationships and improve the estimation of critical defect sizes. The approach provides a basis for
Muhammad Muteeb Butt, Varma Kvvssn, Hossein Laieghi, Zia Uddin, Peyman Ansari, E. Kıvanç Sadak, Can Barış Toprak, Hüseyin Kızıl, Enrico Salvati   +8 more
wiley   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source