Results 51 to 60 of about 8,685,496 (352)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Optimal Configuration for Photovoltaic and Energy Storage in Distribution Network Using Comprehensive Evaluation Model

Energies
To enhance the efficiency of renewable energy consumption and reduce reliance on fossil fuels, the study addresses the challenges of distributed photovoltaic and energy storage integration in distribution networks, such as voltage fluctuations, safety ...
Rui Gao, Dan Wang, Chengxiong Mao, Bin Liu, Bingzhao Zhu, Jiawei Huang, Shengjun Wu   +6 more
doaj   +1 more source

Grid interoperability solutions in grid resource management

, 2009
Since the management and beneficial utilization of highly dynamic grid resources cannot be handled by the users themselves, various grid resource management tools have been developed, supporting different grids.
Kertesz, A., Kacsuk, P.
core   +1 more source

Using high-level petri nets for hierarchical grid workflows

, 2022
S.13An increasingly popular application programming model for Grids is to deploy often-used functionalities as remote services on high-performance hosts, following the principles of a service-oriented architecture.
Pohl, H.-W., Alt, M., Hoheisel, A., Gorlatch, S.   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Modeling and Control of Grid Forming Converters: A Systematic Review

IEEE Access
In electrical power systems where the proportion of synchronous generators (SG) is gradually decreasing, grid-forming (GFM) converters need to be installed and controlled to meet all the system requirements that SGs have provided to date.
Macit Tozak, Sezai Taskin, Ibrahim Sengor, Barry P. Hayes   +3 more
doaj   +1 more source

Grid-based semantic integration of heterogeneous data resources: Implementation on a HealthGrid [PDF]

, 2007
This thesis was submitted for the degree of Doctor of Philosophy and was awarded by Brunel University.The semantic integration of geographically distributed and heterogeneous data resources still remains a key challenge in Grid infrastructures. Today's
Naseer, Aisha
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Simulation and application analysis of a hybrid energy storage station in a new power system

Global Energy Interconnection
As the proportion of renewable energy infiltrating the power grid increases, suppressing its randomness and volatility, reducing its impact on the safe operation of the power grid, and improving the level of new energy consumption are increasingly ...
Tianyu Zhang, Xiangjun Li, Hanning Li, hangyu Sun, Weisen Zhao   +4 more
doaj   +1 more source

Optimization of Energy Systems in a Distribution Micro grid: An Application of the Particle Swarm Optimization

Majlesi Journal of Electrical Engineering, 2023
This article proposes a method for optimizing the energy systems in a distribution micro-grid using particle swarm optimization. The method considers the optimal production planning of simultaneous production systems and takes into account the loss of ...
Waleed Khalid Al-Azzawi, Ahmed Kateb Jumaah Al-Nussairi, Hussein Riyadh Taresh, Zainab R. Abdulsada, Kadhum Al-Majdi, Ali H. A, Julayeva Zhazira   +6 more
doaj   +1 more source