Results 91 to 100 of about 984,534 (293)

Exploring Local Optima in Schematic Layout [PDF]

, 2013
In search-based graph drawing methods there are typically a number of parameters that control the search algorithm. These parameters do not affect the ?tness function, but nevertheless have an impact on the ?nal layout. One such search method is hill
Chivers, Daniel, Rodgers, Peter
core  

In search of grid converged solutions

Procedia Engineering, 2010
AbstractAssessing solution error continues to be a formidable task when numerically solving practical flow problems. Currently, grid refinement is the primary method used for error assessment. The minimum grid spacing requirements to achieve design order accuracy for a structured-grid scheme are determined for several simple examples using truncation ...
openaire   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

Safe Grid Search with Optimal Complexity

, 2018
Popular machine learning estimators involve regularization parameters that can be challenging to tune, and standard strategies rely on grid search for this task. In this paper, we revisit the techniques of approximating the regularization path up to predefined tolerance $ $ in a unified framework and show that its complexity is $O(1/\sqrt[d] )$ for ...
Ndiaye, Eugene, Le, Tam, Fercoq, Olivier, Salmon, Joseph, Takeuchi, Ichiro   +4 more
openaire   +2 more sources

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Comparative Analysis of ARIMA and LSTM for Forecasting Maximum Wind Speed in Kupang City, East Nusa Tenggara

Jambura Journal of Mathematics
This study compares the Autoregressive Integrated Moving Average (ARIMA) and Long Short-Term Memory (LSTM) models for predicting maximum wind speed based on accuracy measured by Root Mean Square Error (RMSE) and Mean Absolute Percentage Error (MAPE ...
Indah Magfirrah, Meisyatul Ilma, Khairil Anwar Notodiputro, Yenni Angraini, Laily Nissa Atul Mualifah   +4 more
doaj   +1 more source

Towards data grids for microarray expression profiles [PDF]

, 2006
The UK DTI funded Biomedical Research Informatics Delivered by Grid Enabled Services (BRIDGES) project developed a Grid infrastructure through which research into the genetic causes of hypertension could be supported by scientists within the large ...
Bayliss, C., Sinnott, R.O.
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Accurate Grid-based Clustering Algorithm with Diagonal Grid Searching and Merging

IOP Conference Series: Materials Science and Engineering, 2017
Due to the advent of big data, data mining technology has attracted more and more attentions. As an important data analysis method, grid clustering algorithm is fast but with relatively lower accuracy. This paper presents an improved clustering algorithm combined with grid and density parameters.
Feng Liu, Chengcheng Ye, Erzhou Zhu
openaire   +1 more source

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source