Results 171 to 180 of about 12,297 (303)

Microtopography enhances intestinal drug absorption via Piezo1‐mediated tight junction modulation

open access: yesBMEMat, EarlyView.
Microtopography‐driven enhancement of oral peptide drug delivery by activating Piezo1 channels significantly improves paracellular permeability and bioavailability, offering a novel approach for optimizing macromolecule absorption in pharmaceutical formulations.
Yu Hu   +12 more
wiley   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

open access: yesBMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing   +6 more
wiley   +1 more source

Design and control of LCC DVR. [PDF]

open access: yesSci Rep
Manju AS, Manitha PV, Nair MG, Joseph A.
europepmc   +1 more source

Shaping Energy Transitions: Sectoral Demand, Climate Risk Exposure, and Renewable Pathways in Sub‐Saharan Africa

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Energy is a fundamental driver of economic growth, shaping productivity, industrialization, and long‐term economic resilience. In sub‐Saharan Africa (SSA), where energy access remains uneven and infrastructure is underdeveloped, understanding sector‐specific energy demand is essential for designing sustainable energy strategies.
Michael Appiah   +3 more
wiley   +1 more source

Addressing the Energy Trilemma: The Role of Entrepreneurship, Regulation, and Climate Finance

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Balancing energy security, energy equity, and environmental sustainability has become increasingly challenging as economies pursue low‐carbon growth amid climate risk and persistent disparities in access to modern energy. Although entrepreneurship is widely recognized as a driver of innovation, its role in addressing the energy trilemma ...
Kingsley Imandojemu   +3 more
wiley   +1 more source

Why Are Consumers Ambivalent About AI‐Generated Images? The Moderating Role of Commercial Versus Noncommercial Content Type

open access: yesJournal of Consumer Behaviour, EarlyView.
ABSTRACT Grounded in ambivalence theories, this research examined factors shaping consumer ambivalence toward AI‐generated content and investigated differences between commercial and noncommercial contexts. As a preliminary study, sentiment analysis of Reddit data using a support vector machine (SVM) revealed that most consumer sentiment toward AI ...
Garim Lee   +3 more
wiley   +1 more source

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