Results 151 to 160 of about 13,489 (291)

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

Emergence of a novel reassorted high pathogenicity avian influenza A(H5N2) virus associated with severe pneumonia in a young adult. [PDF]

Sci Rep
Vázquez-Pérez JA, Becerril-Vargas E, Ramírez-González JE, Solís-Hernández M, Davis CT, Garciadiego-Fossas P, Villanueva-Reza M, Chávez-Morales HH, Mendoza-Ramírez E, Olivares-Flores CD, Vera-Jiménez AC, Rumbo-Nava U, Guadarrama-Pérez C, Recinos-Carrera EG, Zúñiga J, López-Martínez I, Hernández-Rivas L, Barrera-Badillo G, Colin-Soto N, Flores-Cisneros L, Carbajal-Sandoval G, Vidal-Aguirre D, Arellano-Suarez DS, Aparicio-Antonio R, López-Elizalde R, Alcazar-Ramiro CJ, García-López A, Di H, Kirby M, Jang Y, Lezana-Fernández MA, Hernández-Cárdenas CM.   +31 more
europepmc   +1 more source

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

Advanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand, Muhamet Ibrahimi, Claire Valotteau, Brice Lecouffe, André Le Bivic, Dominique Massey‐Harroche, Felix Rico, Matthias Merkel, Delphine Delacour, Elsa Bazellières   +9 more
wiley   +1 more source

Post-Infectious Syndromes in the Post-Pandemic Phase Among the German General Population. [PDF]

Dtsch Arztebl Int
Frost J, Peter F, Glaser N, Frese T, Heuser M, Gekle M, Girndt M, Opel N, Behrens T, Karch A, Muellmann S, Zeeb H, Tüscher O, Mikolajczyk R.   +13 more
europepmc   +1 more source

Bilayered PEDOT:PSS–Collagen Scaffolds as Functional Architectures for Tissue Engineering

Advanced Materials Interfaces, EarlyView.
A bilayered scaffold integrates collagen and PEDOT:PSS as distinct yet interconnected 3D matrices, preserving their fibrillar and conductive characteristics. Spatial compartmentalization enables independent tailoring of each domain while maintaining mechanical stability and compatibility with electrochemical monitoring, providing a multifunctional ...
Rasha Nasser, Jiranuwat Sapudom, Sotiris Psilodimitrakopoulos, Emmanuel Stratakis, Jeremy Teo, Vincent Chan, Charalampos Pitsalidis   +6 more
wiley   +1 more source

Smiling Tremor in a Patient with Essential Tremor. [PDF]

Mov Disord Clin Pract
Chen JC, Grippe T, Mahjoub Y, Kleiner G, Chen R.   +4 more
europepmc   +1 more source

That awful grippe the gods let slip

, 1958
voiceCollected by Ruth Jolly And Don Stone For Mary C. Parler Sung by Otis Williams Wesley, Arkansas December 4, 1958 Transcribed by Frances Majors That awful grippe the gods let slip Upon me last week Sunday, No faster than racked my farm E'er swept the
Williams, Otis
core  

Control of Bacterial Attachment on Macroporous PDMS/Paraffin SLIPS With Varying Lubricant Viscosity

Advanced Materials Interfaces, EarlyView.
Slippery liquid‐infused porous surfaces (SLIPS) prepared from macroporous PDMS, infused with medical‐grade paraffins, were systematically investigated regarding the correlation of viscosity, surface corrugation, bulk porosity, and bacterial resistance. Substrate porosity was found to dominate lubricant stabilization and the antifouling activity.
Regina Kopecz, Sabrina A. Böer, Onur Özcan, Axel Rosenhahn   +3 more
wiley   +1 more source

Tics and Tic-Like Phenomena as Compulsive Acts. [PDF]

Mov Disord Clin Pract
Grippe T, Chen JC, Balachandar A, Reyes NGD, Sandor P, Lang AE, Ganos C.   +6 more
europepmc   +1 more source

A U‐shaped Microfluidic Platform for Culturing Vascularized Colorectal Cancer Spheroids Reveals Tumor–Endothelial Crosstalk and Invasion‐Associated Remodeling

Advanced Materials Technologies, EarlyView.
A closed U‐shaped microfluidic platform symmetrically embeds a single, size‐controlled HT29 colorectal cancer spheroid within a GFP‐HUVEC‐laden fibrin matrix. HT29 spheroids are associated with hyper‐branched endothelial network remodeling, while vascularized co‐culture is accompanied by anisotropic protrusive growth and EMT‐like marker changes in the ...
G. Cretti, M. Ballerini, A. Mantegazza, P. Occhetta, M. Rasponi   +4 more
wiley   +1 more source