Results 201 to 210 of about 35,270 (239)
Some of the next articles are maybe not open access.
GPCR signalling in hypertension: role of GRKs
Clinical Science, 2008Hypertension is a prevalent condition in the developed world and disease severity is directly correlated with additional cardiovascular complications. It is estimated that 30% of the adult population in the United States has hypertension, which is classified as a systolic blood pressure ≥140 mmHg and/or a diastolic blood pressure ≥90 mmHg.
David M, Harris +3 more
openaire +2 more sources
Science Signaling, 2018
The dopamine D2 receptor recruits and activates the kinase GRK2 without the need for G protein activation.
openaire +1 more source
The dopamine D2 receptor recruits and activates the kinase GRK2 without the need for G protein activation.
openaire +1 more source
Science Signaling, 2009
Hedgehog promotes the interaction of G protein–coupled receptor kinase with Patched, releasing cyclin B1 to stimulate cell proliferation.
openaire +1 more source
Hedgehog promotes the interaction of G protein–coupled receptor kinase with Patched, releasing cyclin B1 to stimulate cell proliferation.
openaire +1 more source
Science Signaling, 2008
G protein-coupled receptor kinase 5 (GRK5) phosphorylates HDAC5, thus allowing the transcription of genes involved in cardiac hypertrophy.
openaire +1 more source
G protein-coupled receptor kinase 5 (GRK5) phosphorylates HDAC5, thus allowing the transcription of genes involved in cardiac hypertrophy.
openaire +1 more source
[GRKs and arrestins: the therapeutic pathway?].
Medecine sciences : M/S, 2006Phosphorylation of the agonist-activated form of G-protein-coupled receptors (GPCRs) by a protein kinase from the G-protein-coupled receptor kinase (GRK) family initiates, with arrestin proteins, a negative feedback process known as desensitization.
Thierry, Métayé +2 more
openaire +1 more source
Regulation of Receptor Tyrosine Kinase Signaling by GRKs and β-Arrestins
Annual Review of Physiology, 2007Receptor tyrosine kinases (RTKs) are a unique family of cell surface receptors, each containing a common intracellular domain that has tyrosine kinase activity. However, RTKs share many signaling molecules with another unique family of cell surface receptors, the seven-transmembrane receptors (7TMRs), and these receptor families can activate similar ...
Christopher J, Hupfeld +1 more
openaire +2 more sources
GRKs and β-arrestins: roles in receptor silencing, trafficking and signaling
Trends in Endocrinology & Metabolism, 2006Stimulation of cell-surface seven-transmembrane receptors (7TMRs) elicits biological responses to a wide range of extracellular signals, including many hormones. Classically, heterotrimeric GTP-binding proteins (G proteins) are recruited to the activated conformation of 7TMRs.
Reiter, Eric, Lefkowitz, J.
openaire +2 more sources
GRK Gatekeeper of pain and inflammation
2009More then 10% of the population suffers from chronic pain. Treatment often fails since individual susceptibility is highly variable. Therefore, better understanding of factors involved in determination whether pain becomes chronic is crucial. In this thesis we investigated the role of two kinases, G protein-coupled receptor kinase (GRK) 2 and 6, as ...
Eijkelkamp, N. +4 more
openaire +2 more sources
Zaštita geografskog podrijetla kvalitetnog vina "Grk"
1982U elaboratu su prikazani rezultati zaštite geografskog podrijetla kvalitetnog vina "Grk"
Pezo, Ivan, Maleš, Petar
openaire +2 more sources
Unaprjeđenje tehnologije proizvodnje grožđa cv. Grk
2010Rad sadržava pregled stanja tla u vinogradima i ishranjenost vinove loze cv. Grk, utvrđivanje zdravstvenog stanja te bioloških i gospodarskih karaketristika cv. Grk.
Romić, Marija +10 more
openaire +2 more sources