Results 151 to 160 of about 80,126 (312)

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

Interdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li, Ai Chen, Chen Zhang, Meihong Da, Yonghui Liu, Zhi He, Chenyan Yuan, Shuo Ma, Yuming Yao, Dawen Chen, Meiling Zhou, Zhixin Song, Wenjing Lu, Chun‐Kwok Wong, Guoqiu Wu, Xun Gao   +15 more
wiley   +1 more source

Bioinorganic Site‐Specific Conjugation of Multi‐Arm Linkers to Create Pharmaceuticals With Targeting and Effector Functions

Journal of the Chinese Chemical Society, EarlyView.
This Account showcases a modular, multi‐arm linker platform that decouples payload loading from antibody conjugation. By leveraging a computationally designed ACPGHA zinc‐binding motif, we demonstrate the construction of homogeneous antibody‐drug conjugates and theranostic antibody‐radionuclide conjugates with high payload loading. The multi‐arm linker
Cédric Grauffel, Tse Wen Chang, Carmay Lim   +2 more
wiley   +1 more source

3-D numerical modelling of flow around a groin

, 2003
A 3-D flow code, EllipSys3D, has been implemented to simulate the 3-D flow around a groin in steady current. The k turbulence model has been used for closure.
Michelsen, Jess, Miller, R., Roulund, A., Truelsen, Christoffer, Sumer, B. Mutlu, Fredsøe, Jørgen   +5 more
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Is the Cognitive Ability of Fawn‐Footed Mosaic‐Tailed Rat Melomys cervinipes Offspring Related to Mothers’ Care or Cognitive Abilities?

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT The cognitive abilities of many non‐human animals have been investigated in recent years; however, outside of laboratory rodent strains, it is largely unknown how direct and indirect genetic factors influence the development of cognition. In a previous study, we found no impact of maternal genetic or non‐genetic effects on problem solving in ...
Misha K. Rowell, Tasmin L. Rymer
wiley   +1 more source

Movable-Bed Model Investigation of Groin Notching

, 2004
Groin notching, the purposeful lowering of a portion of the structure to promote controlled movement of sand alongshore, has been implemented for evaluation along the New Jersey coast by the U.S. Army Corps of Engineers.
Kraus, Nicholas C., Wang, Ping
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Groin abscess outside the hernia sac secondary to perforated appendicitis in an older adult: a case report. [PDF]

J Surg Case Rep
Okamoto N, Furukawa T, Hirano T, Nagamine I, Otagaki S, Takahashi S.   +5 more
europepmc   +1 more source

Juvenile Mycosis Fungoides: A Multicenter Retrospective Italian Study

JEADV Clinical Practice, EarlyView.
This multicenter retrospective study included 29 juvenile mycosis fungoides (JMF) patients from five Italian centres with confirmed histopathological diagnosis. most often presents with hypopigmented/classic variants and CD8+ phenotype. Early‐onset cases ( < 14 years) show better long‐term outcomes.
Andrea Michelerio, Gabriele Roccuzzo, Iria Neri, Alessandro Pileri, Alessandro Svizzero, Maria Beatrice De Felici Del Giudice, Vieri Grandi, Pietro Quaglino, Valeria Brazzelli   +8 more
wiley   +1 more source

Ultrasound Screening for Cam Morphology in Male University Soccer Players: Prevalence and Association With Groin Symptoms and Functional Impairments. [PDF]

Orthop J Sports Med
Saito M, Utsunomiya H, Yamashita R, Hattori M, Tomioka Y, Tateishi T, Kusakabe T, Ogawa H, Hirasawa N, Tsukada S.   +9 more
europepmc   +1 more source

Isotretinoin and Hidradenitis Suppurativa a Conflictual Binomial: Investigation on Differential Response Rate Between Inflammatory and Follicular Phenotype

JEADV Clinical Practice, EarlyView.
A cohort of 21 HS patients treated with isotretinoin was enrolled in this study. The main outcome was HISCR50 achievement at week 16. Overall, 2/12 patients affected by follicular phenotype of HS and 2/9 patients affected by inflammatory phenotype of HS achieved HISCR50 at week 16. No significant difference was found in response to isotretinoin between
Maria Vittoria Cannizzaro, Flaminia Antonelli, Dalma Malvaso, Federica Pellegrini, Elena Ippoliti, Niccolò Gori, Ketty Peris   +6 more
wiley   +1 more source

Groin Pain

, 2001
Entezitis tetiva aduktora longusa i/ili trbušnih mišića definiramo kao sindrom bolne prepone. Jedan od čestih uzroka nastanka sindroma bolne prepone jest slabost trbušne stijenke. Za nj danas postoji uvriježeni naziv sportska hernija.
Damir Hudetz, Hudetz, Damir, Janković, Saša, Delimar, Domagoj, Domagoj Delimar, Saša Janković   +5 more
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