Results 211 to 220 of about 192,039 (239)

QSAR-Guided Virtual Screening and Molecular Dynamics Reveal Olaparib as a Repurposing Lead Against α-Synuclein Aggregation. [PDF]

Int J Mol Sci
Abdelsayed M, Boulaamane Y.
europepmc   +1 more source

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

Angewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang, Heli Tirkkonen, Sabina Y. van der Zanden, Larissa Ponomareva, Isaline Fagon, Leslie Fève, Kendall Paige, Courtney L. Brown, Nora Schwartz, Jacob Hecht, Jennifer Nguyen, Jon S. Thorson, Jacques Neefjes, S. Eric Nybo, Khaled A. Shaaban, Mikko Metsä‐Ketelä   +15 more
wiley   +1 more source

Drude SILCS-Nucleic: harnessing explicit electronic polarization in targeting RNA and DNA for drug design. [PDF]

Nucleic Acids Res
Michel HM, Brown AM, MacKerell AD, Lemkul JA.   +3 more
europepmc   +1 more source

Fracture Risk Evaluation of Trochlear Groove Depth in Toy and Small-Breed Dogs Under Gait-Based Loading: A Finite Element and Fatigue Analysis Study. [PDF]

Animals (Basel)
Jeong M, Woo HM, Kim K, Kim J.
europepmc   +1 more source

Combined Interhemispheric and Endoscopic Endonasal Resection of a Rare Olfactory Schwannoma with Preservation of Olfactory Function. [PDF]

Curr Oncol
Anselmi L, Lavé A, Egervari K, Landis BN, Bijlenga P, Hsieh JW, Constanthin PE.   +6 more
europepmc   +1 more source

Controllable Surface Structures of Hydroxyapatite Processed by Picosecond Laser in Air and Underwater: A Comparative Study of Experiment and Simulation. [PDF]

Materials (Basel)
Liu L, Yao P, Chu D, Qu S, Huang C.
europepmc   +1 more source

Electrochemical DNA hairpin sensors for differentiating small molecule intercalation from minor groove binding.

Sens Diagn
Thompson K, Barnes K, Yoseph S, Clark V, Mahlum JD, Majumdar A, Lukeman PS, Arroyo-Currás N.   +7 more
europepmc   +1 more source

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An experimental investigation of flow boiling characteristics in silicon-based groove-wall microchannels with different structural parameters

International Journal of Heat and Mass Transfer, 2021
Yuanpeng Yao, Huiying Wu
exaly