Results 111 to 120 of about 2,432 (198)

Multi‐Omics‐Guided Design and Safety Engineering of Nucleic Acid Therapeutics: From Molecular Perturbation to Predictive Toxicology and Precision Translation

Chemical Biology &Drug Design, Volume 108, Issue 2, August 2026.
Multi‐omics (proteomics, metabolomics, and single‐cell/spatial transcriptomics) provides a systems framework to distinguish on‐target efficacy from off‐target and toxicity signatures of chemically modified nucleic acid therapeutics, enabling omics‐guided structure–activity and safety optimisation from discovery to clinical translation. ABSTRACT Nucleic
Gurjit Kaur Bhatti, Anushka Verma, Komal Devi, Naina Khullar, Inderpal Singh Sidhu, Umesh Chand Singh Yadav, Jasvinder Singh Bhatti   +6 more
wiley   +1 more source

Abstracts

Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

An experimental examination of dispersal decisions made by flight‐capable heteropteran insects in urban stormwater pond conditions

Ecological Entomology, Volume 51, Issue 4, Page 672-689, August 2026.
Salty conditions in urban stormwater ponds can influence dispersal timing in species‐specific ways for actively dispersing aquatic heteropteran insects. Assaying multiple aspects of dispersal propensity, Hesperocorixa obliqua emigrated earlier in stormwater pond conditions while overall probabilities remained unchanged; Notonecta undulata emigration ...
Ilia Maria C. Ferzoco, Shannon J. McCauley   +1 more
wiley   +1 more source

[Giant laterocervical lipoma in a 6-month-old infant: a case report]. [PDF]

Pan Afr Med J
Niang CD, Sarr MC, Ba M, Toko B, Barry M, Fall F, Niang F, Thiam I, Diouf MS.   +8 more
europepmc   +1 more source

Towards the Prevention of Freezing of Gait in Parkinson's Disease

European Journal of Neuroscience, Volume 64, Issue 4, August 2026.
Freezing of gait (FOG) is a disabling complication of Parkinson's disease (PD) that remains difficult to treat. Targeting modifiable risk factors and implementing pleiotropic (lifestyle) interventions before FOG onset may potentially delay or prevent its development.
Anouk Tosserams, Jorik Nonnekes, Bastiaan R. Bloem, Elbrich M. Postma   +3 more
wiley   +1 more source

Why was the treatment discontinued? Reasons for attrition in evidence-based trauma-focused treatments. [PDF]

Eur J Psychotraumatol
Glad KA, Ekroll VB, Egeland K, Bækkelund H.   +3 more
europepmc   +1 more source

Disproportionate organizational injustice: a close look at facilities exempted from indoor smoking laws in Canada. [PDF]

Healthc Policy, 2012
Al-Hamdani M.
europepmc   +1 more source

Inbreeding and Demographic History of Caribou (Rangifer tarandus) in Western Canada Inferred From Genome‐Wide SNP Data

Evolutionary Applications, Volume 19, Issue 8, August 2026.
ABSTRACT Assessing genetic diversity is essential for conserving endangered populations, yet comprehensive genomic evaluations remain limited for many declining species. Here, we investigated inbreeding levels and effective population sizes (Ne) of caribou (Rangifer tarandus) in western Canada, where populations have experienced pronounced declines ...
Charlotte Bourbon, Samuel Deakin, Anita Michalak, Margaret M. Hughes, Maria Cavedon, Lalenia Neufeld, Agnès Pelletier, Jean Polfus, Helen Schwantje, Caeley Thacker, Marco Musiani, Jocelyn Poissant   +11 more
wiley   +1 more source

Use of artificial intelligence for reverse referral between a hospital emergency department and a primary urgent care center. [PDF]

Front Digit Health
Taules Y, Gros S, Viladrosa M, Llorens N, Solis S, Yuguero O.   +5 more
europepmc   +1 more source

Gros plan « 2015, année de l'enseignement » ?

, 2015
À partir d’un regard diachronique sur le cas mauritanien, en nous appuyant sur les travaux de collègues et nos propres terrains, il est tout simplement question dans ce gros plan de présenter brièvement les grandes étapes de la (dé)structuration de l’enseignement et du système scolaire mauritanien et de montrer combien l’enseignement, malgré de ...
openaire   +1 more source