Results 41 to 50 of about 109,285 (263)

Experimental Investigation of a 300 kW Organic Rankine Cycle Unit with Radial Turbine for Low-Grade Waste Heat Recovery

open access: yesEntropy, 2019
The performance of a 300 kW organic Rankine cycle (ORC) prototype was experimentally investigated for low-grade waste heat recovery in industry. The prototype employed a specially developed single-stage radial turbine that was integrated with a semi ...
Ruijie Wang   +4 more
doaj   +1 more source

Space Efficiency in Finnish Mid-Rise Timber Apartment Buildings

open access: yesBuildings, 2023
As in many other building types, space efficiency in mid-rise timber apartment buildings is one of the critical design parameters to make a project feasible.
Antti Tuure, Hüseyin Emre Ilgın
doaj   +1 more source

Reliability of Cycling Gross Efficiency Using the Douglas Bag Method [PDF]

open access: yesMedicine & Science in Sports & Exercise, 2012
The aim of this study was to establish the reliability of gross efficiency (GE) measurement (the ratio of mechanical power input to metabolic power output, expressed as a percentage) using the Douglas bag method.The experiment was conducted in two parts.
Hopker, James G.   +4 more
openaire   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Determining the Efficiency and Inefficiency Intervals of Crop Production in Iran [PDF]

open access: yesپژوهشهای اقتصادی, 2020
In this study, using the classic and developed models of data envelopment analysis, the frontiers of efficiency and inefficiency were determined for 29 irrigated crops and the relative position of products was determined in terms of gross income and ...
ali shahnavazi
doaj  

Identification of a general light use efficiency model for gross primary production [PDF]

open access: yesBiogeosciences, 2011
Non-stationary and non-linear dynamic time series analysis tools are applied to multi-annual eddy covariance and micrometeorological data from 44 FLUXNET sites to derive a light use efficiency model for gross primary production on a daily basis.
J. E. Horn, K. Schulz
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

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