Results 61 to 70 of about 55,148 (240)

Generation of Self‐Organizing Macrovascular Constructs by Bioprinting Human iPSC‐Derived Mesodermal Progenitor Cells

Advanced Science, EarlyView.
ABSTRACT Vascularization remains a major obstacle in tissue engineering. Here, we introduce a bioprinting strategy to generate centimeter‐scale, self‐organizing “mother vessel” constructs from iPSC‐derived hiMPCs. By optimizing bioink composition, printing was accomplished in a single‐step approach. Within one week, hiMPCs differentiated into both CD31+
Leyla E. Dogan, Nathaly A. Chicaiza‐Cabezas, Florian Kleefeldt, Philipp Wörsdörfer, Jürgen Groll, Süleyman Ergün   +5 more
wiley   +1 more source

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

Stiffness‐Activated Stellate Cells Drive Pancreatic Cancer Liver Colonization via GMFG‐TNS4 Signaling

Advanced Science, EarlyView.
Fibrotic liver stiffness activates hepatic stellate cells through Piezo1‐dependent calcium influx and ER stress, promoting EV‐associated GMFG release. Delivered GMFG engages TNS4 in pancreatic cancer cells, triggering FAK/AKT signaling, adhesion, and fatty acid synthesis.
Biwen Zhu, Jian Wan, Xue Zhang, Jiashuai Yan, Xi Chen, Xiaoqi Guan, Qianqian Ren, Tao Yang, Di Wu, Qingsong Guo, Yibing Guo, Yuhua Lu   +11 more
wiley   +1 more source

STRATEGI BERSAING PADA RANTAI NILAI AYAM RAS PEDAGING PT CIOMAS ADISATWA REGION JAWA BARAT UNIT BOGOR

Jurnal Manajemen & Agribisnis, 2014
The objective of this research were to 1) map the broiler value chain at PT Ciomas Adisatwa Region Jawa Barat Unit Bogor (PTCA); 2) analyze the gross margin of the broiler value chain at PTCA; 3) identify the internal and external factors that affecting ...
Muhammad Hasan Tanjung, Arief Daryanto, Muladno Muladno   +2 more
doaj   +1 more source

Correcting Apparent Priming Bias Unveils Fertilizer Nitrogen‐Risk Archetypes of Surplus and Depletion Across Asian Rice Systems

Advanced Science, EarlyView.
Correcting the apparent priming effect resolves systematic biases in Asian rice fertilizer nitrogen accounting. Net soil retention drops below 7%, while 48% of fertilizer escapes, inflicting US$98.53 billion in annual reactive‐nitrogen damages. High‐resolution mapping uncovers N‐risk archetypes across 42% of the rice area, delivering a spatially ...
Xiuyun Liu, Siyuan Cai, Longlong Xia, Jagdish K. Ladha, Xiaoyuan Yan, Xu Zhao   +5 more
wiley   +1 more source

Morula Kernel Cake (Sclerocarya birrea) as a Protein Source in Diets of Finishing Tswana Lambs: Effects on Nutrient Digestibility, Growth, Meat Quality, and Gross Margin. [PDF]

Animals (Basel), 2023
Baleseng L, Madibela O, Tsopito C, Mareko M, Boitumelo W, Letso M.   +5 more
europepmc   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Market participation and profitability of small scale garri processing in Edo, Ogun and Oyo States, Nigeria

Journal of Agriculture and Rural Development in the Tropics and Subtropics
Nigeria is the largest producer of cassava which is a staple food crop consumed in different forms. garri is one of the products commonly consumed by households.
Jelili Olaide Saka, Veronica Adeoti Obatolu, Bosede Olukemi Lawal, Ayodeji Babatunde Idowu, Chukwudi Peter Amadi, Johnson Adedayo Adetumbi, Taofik Oyedele Dauda   +6 more
doaj   +1 more source

A gross margin analysis for Nguni cattle farmers in Limpopo Province, South Africa. [PDF]

PLoS One, 2021
Nkadimeng MV, Makombe G, Mapiye O, Mapiye C, Oluwatayo I, Dzama K, Mojapelo C, Mollel N, Ngambi J, Mautjana MH.   +9 more
europepmc   +1 more source

Efficient Adsorption‐Based Direct Air Capture Via Triply Periodic Minimal Surface Architectures

Advanced Science, EarlyView.
Architected triply periodic minimal surface (TPMS) contactors reshape direct air capture by replacing straight‐channel diffusion limits with convection‐enhanced CO2 transport. Chaotic advection thins boundary layers and exposes fast adsorption sites, enabling 70%–75% more fast sites, 114% higher productivity, and 51.8% lower energy consumption than ...
Qingyang Shao, Zhuozhen Gan, Chengcheng Long, Man Zhang, Yihe Miao, Yuehui Li, Xuancan Zhu   +6 more
wiley   +1 more source