Results 171 to 180 of about 215,712 (346)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Nanoscale Mapping of the Subcellular Glycosylation Landscape

Advanced Science, EarlyView.
Using multiplexed super‐resolution imaging with fluorophore‐labeled lectins, this study reports intracellular glycosylation at the nanoscale across organelles and synaptic specializations. Extending glycan analysis beyond the cell surface, Glyco‐STORM reveals distinct glycosylation nanodomains in the ER, Golgi, lysosomes, and synaptic sites.
Helene Gregoria Schroeter, Steffen Sass, Mike Heilemann, Thomas Kuner, Maja Klevanski   +4 more
wiley   +1 more source

International trade and individual labour market perspectives: A micro-level analysis of German manufacturing workers [PDF]

This paper studies the impact of international trade on individual labour market outcomes in the German manufacturing sector for the period 1995-2006. Combining micro-level data from the German Socioeconomic Panel and industry-level trade data from input-
Lurweg, Maren, Uhde, Nicole
core   +3 more sources

Determinants of gross motor skill performance in children with visual impairments.

Research in Developmental Disabilities, 2014
Pamela S. Haibach, Matthias Wagner, L. Lieberman   +2 more
semanticscholar   +1 more source

METTL10‐Mediated PIAS3 Methylation Links Purine Metabolism to Gastric Cancer Progression

Advanced Science, EarlyView.
METTL10‐mediated methylation of PIAS3 at K442 inhibits its SUMO E3 ligase activity toward MITF. This reduces MITF SUMOylation and subsequent RNF4‐mediated ubiquitination, leading to MITF protein accumulation and gastric cancer progression. Abstract Metabolic dysregulation plays a significant role in the development of gastric cancer (GC).
Jinshui Tan, Huiwen Zhou, Jingsong Ma, Chensong Zhang, Yuhua Tan, Baoding Zhang, Jiabao Zhao, Ao Cheng, Chengyu Yang, Meijuan Xu, Shengyi Zhou, Yubo Xiong, Zeyang Lin, Guangchao Pan, Wenjie Ye, Mengya Zhong, Yang Yang, Yifan Zhuang, Shao‐Wei Li, Xianming Deng, Xuehui Hong   +20 more
wiley   +1 more source

Comparing the Students with and without Hyperactive Disability in the Fine and Gross Motor Skill and Sensory Profiling

Salāmat-i ijtimā̒ī, 2018
Background and Objectives: Attention defiit/hyperactivity disorder in childhood is a neurodevelopmental disorder that often continues into adulthood and affects different aspects of life.
Neda Salehi, Mahnaz Esteki
doaj  

DEVELOPMENT OF GROSS MOTOR SKILLS SCREENING TOOL FOR INCLUSIVE EDUCATION

, 2015
Assoc. Prof. Donald S. Lipardo, Assist. Prof. Maripia Rabacal, Mr. Hubert Ramos, Assist. Prof. Ma. Georgina Mojica, Assist. Prof. Karen S. Ongtangco, Assoc. Prof. Marie Ann Vargas, Ms. Marichou Beltran, Mr. Bernard Saldivar, Ms. Eleanor Bahrami Hessari   +8 more
openalex   +1 more source

Single‐Cell Dissection of the Biological Function and Molecular Features Underlying the Micropeptide LSMEM1 in Kidney

Advanced Science, EarlyView.
LSMEM1, an evolutionarily conserved micropeptide with extreme hydrophobicity (aliphatic index═113) and dynamic amphiphilicity (GRAVY═0.017), features a strong α‐helical transmembrane anchor (residues 64‐86). Single‐cell analysis reveals its critical role in renal lipid homeostasis.
Peimin Liu, Hong Zhang, Shanzhi Yang, Jiaoqing Li, Danfeng Wu, Haosen Xu, Huan Jiang, Yi Jing, Guoxiang Jin, Ruobing Liu, Ning Fan, Xiaoyan Bai   +11 more
wiley   +1 more source

Comparison of Motor Skills in Children with Developmental Coordination Disorder and Normal Peers

Iranian Rehabilitation Journal, 2008
Objectives: Developmental Coordination Disorder (DCD) is a motor skill disorder which impacts upon a child, s ability to perform age-appropriate activity of daily living and academic performance.
Sahel Hemmati, Nasrin Amiri, Farin Solemani, Asghar Dadkhah   +3 more
doaj  

Gross motor skill performance in children with and without visual impairments--research to practice.

Research in Developmental Disabilities, 2013
Matthias Wagner, Pamela S. Haibach, L. Lieberman   +2 more
semanticscholar   +1 more source